Clinical Trial Applications - Approved: Filter, Search, and view applications
| # | Protocol No | Study Title | Investigator(s) & Site(s) | Date Approved | |
|---|---|---|---|---|---|
1. |
ECCT/26/03/01 | C1091009 Study A Phase 3, Randomized, Placebo-Controlled, Double-Blinded Trial to Evaluate the Safety, Tolerability, and Immunogenicity of a Multivalent Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Infants |
Principal Investigator(s) 1. Lucas Otieno Tina Site(s) in Kenya 1. Victoria Biomedical Research Institute Kisumu County Referral Hospital (Kisumu county) 2. KEMRI Butere Clinical Research Centre (Kakamega county) 3. Kenya Medical Research Institute Walter Reed Project (Kericho county) 4. Kenya Medical Research Institute (KEMRI) - Centre for Global Health Research (Kisumu county) |
26-08-2026 |
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2. |
ECCT/26/02/02 | REVIVE Study - JOOTRH A randomised, double blinded, placebo-controlled, multicentre trial of azithromycin prophylaxis for advanced HIV disease |
Principal Investigator(s) 1. Loice Achieng Ombajo Site(s) in Kenya 1. Jaramogi Oginga Odinga Teaching and Referral Hospital (JOOTRH) (Kisumu county) |
22-08-2026 |
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3. |
ECCT/26/02/03 | REVIVE Study - KNH A randomised, double blinded, placebo-controlled, multicentre trial of azithromycin prophylaxis for advanced HIV disease |
Principal Investigator(s) 1. Loice Achieng Ombajo Site(s) in Kenya 1. Kenyatta National Hospital (KNH) (Nairobi City county) |
28-09-2026 |
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4. |
ECCT/26/02/04 | RSV IMPACT TRIAL A Phase-IIIb individually randomized, placebo-controlled trial on safety of RSVA/B-preF vaccine in pregnant women and efficacy against severe RSV-associated lower respiratory tract infection (LRTI) in infants. |
Principal Investigator(s) 1. Joyce Uchi Nyiro 2. Makobu Kimani Site(s) in Kenya 1. Kilifi, KEMRI-Centre for Geographic Medicine Research Coast (CGMRC) (Kilifi county) |
28-05-2026 |
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5. |
ECCT/25/12/04 | Floral Study An open-label, multi-centre, rollover study to characterise long-term safety and efficacy of etavopivat in adults, adolescents and children who have sickle cell disease or thalassaemia and have completed a treatment period in an etavopivat study |
Principal Investigator(s) 1. Walter Otieno Site(s) in Kenya 1. Kombewa Clinical Research Center (Kisumu county) 2. KEMRI Kondele Children\'s Hospital (Kisumu county) 3. Center for Research in Therapeutic Sciences (CREATES) (Kisumu county) 4. KEMRI Siaya Clinical Research Annex (Siaya county) 5. KEMRI WALTER REED KERICHO (Kericho county) 6. Getrude\'s Children\'s Hospital (Nairobi City county) |
13-04-2026 |
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6. |
ECCT/25/11/05 | MK-8527-011 Study A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis |
Principal Investigator(s) 1. Dr. Joshua Kimani Site(s) in Kenya 1. Nyanza Reproductive Health Society (NRHS), UNIM Research and Training Centre (URTC) (Kisumu county) 2. Partners for Health and Development in Africa – Sex workers Outreach Program (PHDA – SWOP) Clinic- Nairobi, Kenya (Nairobi City county) 3. Kenya Impact Research and Development Organization (K-IRDO) (Kisumu county) |
05-03-2026 |
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7. |
ECCT/25/12/05 | Floral Study An open-label, multi-centre, rollover study to characterise long-term safety and efficacy of etavopivat in adults, adolescents and children who have sickle cell disease or thalassaemia and have completed a treatment period in an etavopivat study |
Principal Investigator(s) 1. Janet Oyieko Site(s) in Kenya 1. Kombewa Clinical Research Center (Kisumu county) 2. Center for Research in Therapeutic Sciences (CREATES) (Kisumu county) 3. Gertrude\'s Children\'s Hospital (Nairobi City county) 4. KEMRI Siaya Clinical Research Annex (Siaya county) 5. KEMRI WALTER REED KERICHO (Kericho county) 6. KEMRI Kondele Children\'s Hospital (Kisumu county) |
13-04-2026 |
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8. |
ECCT/25/11/07 | MK-8527 as HIV-1 PrEP Protocol Title: A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis |
Principal Investigator(s) 1. John Mark Ayallo 2. Kelvin Jerry Wandera 3. John Okanda 4. Joash Diemo 5. Tobias Odwar 6. Jacob Onyango Site(s) in Kenya 1. Kenya Impact Research and Development Organization (K-IRDO) (Kisumu county) 2. Nyanza Reproductive Health Society (NRHS), UNIM Research and Training Center (URTC) (Kisumu county) 3. Partners for Health and Development in Africa – Sex workers Outreach Program (PHDA – SWOP) (Nairobi City county) |
09-02-2026 |
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9. |
ECCT/25/11/03 | RSV IMPACT TRIAL A Phase-IIIb individually randomized, placebo-controlled trial on safety of RSVA/B-preF vaccine in pregnant women and efficacy against severe RSV-associated lower respiratory tract infection in infants. |
Principal Investigator(s) 1. Nancy A. Otieno 2. Evans M. Ogoti Site(s) in Kenya Kenya Medical Research Institute, Centre for Global Health Research - Siaya (KE1) |
09-02-2026 |
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10. |
ECCT/25/11/01 | COMBO-CONSTELLATION A Phase 3, randomized, double-blind, placebo-controlled trial to evaluate the effect of Bifidobacterium longum subsp. infantis DSM33361(Bifin02) administered together with Lacticaseibacillus rhamnosus GG DSM33156 (LGG®) versus placebo on weight gain in underweight infants |
Principal Investigator(s) 1. Dr. Wilson Muraya Site(s) in Kenya 1. KENYA MEDICAL RESEARCH INSTITUTE- MTWAPA (Kilifi county) 2. Moi University Clinical Research Centre-MUCRU (Uasin Gishu county) 3. Kenya Medical Research Institute (KEMRI) CRDR (Nairobi City county) |
21-06-2026 |
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