Clinical Trial Applications - Approved: Filter, Search, and view applications
| # | Protocol No | Study Title | Investigator(s) & Site(s) | Date Approved | |
|---|---|---|---|---|---|
11. |
ECCT/25/11/07 | MK-8527 as HIV-1 PrEP Protocol Title: A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis |
Principal Investigator(s) 1. John Mark Ayallo 2. Kelvin Jerry Wandera 3. John Okanda 4. Joash Diemo 5. Tobias Odwar 6. Jacob Onyango Site(s) in Kenya 1. Kenya Impact Research and Development Organization (K-IRDO) (Kisumu county) 2. Nyanza Reproductive Health Society (NRHS), UNIM Research and Training Center (URTC) (Kisumu county) 3. Partners for Health and Development in Africa – Sex workers Outreach Program (PHDA – SWOP) (Nairobi City county) |
09-02-2026 |
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12. |
ECCT/25/11/03 | RSV IMPACT TRIAL A Phase-IIIb individually randomized, placebo-controlled trial on safety of RSVA/B-preF vaccine in pregnant women and efficacy against severe RSV-associated lower respiratory tract infection in infants. |
Principal Investigator(s) 1. Nancy A. Otieno 2. Evans M. Ogoti Site(s) in Kenya Kenya Medical Research Institute, Centre for Global Health Research - Siaya (KE1) |
09-02-2026 |
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13. |
ECCT/25/11/01 | COMBO-CONSTELLATION A Phase 3, randomized, double-blind, placebo-controlled trial to evaluate the effect of Bifidobacterium longum subsp. infantis DSM33361(Bifin02) administered together with Lacticaseibacillus rhamnosus GG DSM33156 (LGG®) versus placebo on weight gain in underweight infants |
Principal Investigator(s) 1. Dr. Wilson Muraya Site(s) in Kenya 1. KENYA MEDICAL RESEARCH INSTITUTE- MTWAPA (Kilifi county) 2. Moi University Clinical Research Centre-MUCRU (Uasin Gishu county) 3. Kenya Medical Research Institute (KEMRI) CRDR (Nairobi City county) |
21-06-2026 |
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14. |
ECCT/25/09/01 | VLA1553-404 VLA1553-404: A Pragmatic Randomised Controlled Trial to Evaluate the Effectiveness and Safety of VLA1553 against Chikungunya Virus Disease |
Principal Investigator(s) 1. Prof. Videlis Nduba Site(s) in Kenya 1. KEMRI-MTWAPA (Kilifi county) |
21-01-2026 |
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15. |
ECCT/25/11/06 | MK-8527-011 Study A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis |
Principal Investigator(s) 1. Dr Maricianah Onono Site(s) in Kenya 1. Nyanza Reproductive Health Society (NRHS), UNIM Research and Training Centre (URTC) (Kisumu county) 2. Kenya Impact Research and Development Organization (K-IRDO) (Kisumu county) 3. Partners for Health and Development in Africa – Sex workers Outreach Program (PHDA – SWOP) Clinic- Nairobi, Kenya (Nairobi City county) |
05-03-2026 |
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16. |
ECCT/25/08/05 | Floral roll over study An open-label, multi-centre, rollover study to characterise long-term safety and efficacy of etavopivat in adults, adolescents and children who have sickle cell disease or thalassaemia and have completed a treatment period in an etavopivat study. |
Principal Investigator(s) 1. Dr. Isaac Tsikhutsu Site(s) in Kenya 1. KEMRI WALTER REED KERICHO (Kericho county) 2. Center for Research in Therapeutic Sciences (CREATES) (Kisumu county) 3. KEMRI Siaya Clinical Research Annex (Siaya county) 4. Gertrudes Childrens Hospital (Nairobi City county) 5. KEMRI/ WRAIR-Africa, Kombewa Clinical Research Center (Kisumu county) 6. KEMRI/ WRAIR-Africa, Kombewa Clinical Research Center (Kisumu county) 7. KEMRI Kondele Children\'s Hospital (Kisumu county) |
09-02-2026 |
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17. |
ECCT/25/08/04 | MK-8527-010 PrEP A Phase 3, Randomized, Active-Controlled, Double-blind Clinical Study to Evaluate the Efficacy and Safety of Oral MK-8527 Once-Monthly as HIV-1 Preexposure Prophylaxis in Cisgender Women |
Principal Investigator(s) 1. Nelly Rwamba Mugo Site(s) in Kenya 1. KEMRI-CCR PHRD Thika (Kiambu county) |
25-11-2025 |
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18. |
ECCT/25/08/06 | MK-8527-010 A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis in Women |
Principal Investigator(s) 1. Irene Wambui Inwani Site(s) in Kenya 1. UW-KNH; Rachuonyo County Hospital, Oyugis (Homa Bay county) 2. KEMRI-CMR-RCTP KEMRI CIS Building (Kisumu county) 3. Kargeno Research & Policy Hub (Kisumu county) 4. KEMRI-CCR-PHRD, Thika site (Kiambu county) |
15-12-2025 |
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19. |
ECCT/25/11/04 | Bifin02 and LGG® A Phase 3, randomized, double-blind, placebo-controlled trial to evaluate the effect of Bifidobacterium longum subsp. infantis DSM33361(Bifin02) administered together with Lacticaseibacillus rhamnosus GG DSM33156 (LGG®) versus placebo on weight gain in underweight infants |
Principal Investigator(s) 1. Charity Wambui Kanyoro Site(s) in Kenya 1. Moi University Clinical Research (Uasin Gishu county) 2. Kenya Medical Research Institute (KEMRI) CRDR Off Raila Odinga, Nairobi Kenya (Nairobi City county) 3. Kenya Medical Research Institute (KEMRI) Mwtapa (Kilifi county) |
19-08-2026 |
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20. |
ECCT/25/07/08 | REACH Heat-stable carbetocin for the treatment of postpartum haemorrhage: a phase III, randomized, double-blind, active controlled, multicountry, multicentre, non-inferiority trial |
Principal Investigator(s) 1. Zahida Qureshi Site(s) in Kenya 1. Machakos county hospital (Machakos county) 2. Pumwani maternity hospital (Nairobi City county) 3. Nakuru Level 5 Hospital (Nakuru county) |
17-12-2025 |
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