Clinical Trial Applications - Approved: Filter, Search, and view applications
| # | Protocol No | Study Title | Investigator(s) & Site(s) | Date Approved | |
|---|---|---|---|---|---|
171. |
ECCT/23/06/02 | IMAGINE-TBM A Phase II, Randomized, Open-Label Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents with Tuberculous Meningitis: Improved Management with Antimicrobial AGents Isoniazid rifampiciN LinEzolid for TBM (IMAGINE-TBM). |
Principal Investigator(s) 1. Deborah Chepng\'eno Langat Site(s) in Kenya KEMRI/WRP CRC |
24-10-2023 |
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172. |
ECCT/23/06/01 | BREATHE Building Respiratory Support in East Africa Through High Flow versus Standard Flow Oxygen Evaluation |
Principal Investigator(s) 1. Elisabeth Riviello Site(s) in Kenya 1. AIC Kijabe Hospital, Kiambu County (Kiambu county) 2. Nakuru Level 6 Hospital (Nakuru county) |
04-10-2023 |
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173. |
ECCT/23/06/04 | ARNASA A PHASE III, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ASTEGOLIMAB IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE |
Principal Investigator(s) 1. Dr Jacqueline Mirera Site(s) in Kenya 1. Clinical Research Health Network (CREA-N) (Machakos county) 2. KEMRI-CRDR Siaya Clinical Research Annex (Siaya county) 3. KEMRI-Mtwapa Clinical Annex (Kilifi county) 4. Center for Research In Tropical Medicine and Community Development (Nairobi City county) 5. Center for Research In Tropical Medicine and Community Development (Nairobi City county) 6. University of Nairobi Clinical Research Centre (Nairobi City county) 7. KEMRI-CRDR Clinical Research Annex (Nairobi City county) |
24-08-2023 |
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174. |
ECCT/23/10/07 | Fermented Food and Prediabetes A Study of the Hypoglycemic Effect of African Traditonal Fermented Foods amongst Prediabetic Adults. |
Principal Investigator(s) 1. Rosebella Iseme - Ondiek Site(s) in Kenya 1. Aga Khan Outreach Centre Nairobi CBD/Town (Nairobi City county) 2. Aga Khan Outreach Centre Valley Arcade (Nairobi City county) 3. Aga Khan Outreach Centre Capital Centre (Nairobi City county) 4. Aga Khan Outreach Centre Kiambu Town (Kiambu county) 5. Aga Khan Outreach Centre Juja (Kiambu county) 6. Aga Khan Outreach Centre Ruiru (Kiambu county) 7. Aga Khan Outreach Centre Ongata Rongai (Kajiado county) 8. Aga Khan Outreach Centre Ngong (Kajiado county) 9. Aga Khan Outreach Centre Kitengela (Kajiado county) |
17-01-2024 |
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175. |
ECCT/23/05/08 | ACTIV-2d/A5407 A Phase 3, multicenter, randomized, double-blind, 24-week study of the clinical and antiviral effect of S-217622 compared with placebo in non-hospitalized participants with COVID-19 |
Principal Investigator(s) 1. Dr John Kinuthia Site(s) in Kenya 1. Moi University Clinical Research Centre (Uasin Gishu county) 2. Victoria Biomedical Research Institute, (Kisumu county) 3. Kenyatta National Hospital (Nairobi City county) 4. KEMRI CCR – BUTERE SITE (Kakamega county) 5. Kenya Medical Research Institute/Walter Reed Project (Kericho county) 6. KEMRI – AHERO Clinical Trials Unit (Kisumu county) |
27-08-2023 |
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176. |
ECCT/23/04/05 | BiMVaC01 A randomised, controlled clinical trial to assess and compare the immunogenicity, safety and reactogenicity of the bivalent Omicron BA.4/BA.5 adapted, and the original Wuhan-Hu-1-strain, BNT162b2 COVID-19 vaccine formulations in healthy unvaccinated East African adults. |
Principal Investigator(s) 1. NDUNGU FRANCIS 2. Said Jongo Site(s) in Kenya KEMRI-CGMRC Kilifi |
06-07-2023 |
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177. |
ECCT/23/04/03 | ACTIV-2d/A5407 A Phase 3, multicenter, randomized, double-blind, 24-week study of the clinical and antiviral effect of S-217622 compared with placebo in non-hospitalized participants with COVID-19 |
Principal Investigator(s) 1. Prof Abraham Mosigisi Siika Site(s) in Kenya 1. MOI UNIVERSITY CLINICAL RESEARCH CENTRE (Uasin Gishu county) 2. Victoria Biomedical Research Institute, (Kisumu county) 3. Kenyatta National Hospital (Nairobi City county) 4. KEMRI CCR – BUTERE SITE (Kakamega county) 5. Kenya Medical Research Institute/Walter Reed Project (Kericho county) 6. KEMRI – AHERO Clinical Trials Units (Kisumu county) |
14-06-2023 |
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178. |
ECCT/23/05/03 | BrainCapture EEG Validation Usability and efficacy of an affordable, smartphone-connected EEG device to bridge the global gap in epilepsy diagnosis |
Principal Investigator(s) 1. Diraj Sokhi Sokhi Site(s) in Kenya Aga Khan University Hospital Nairobi |
20-12-2023 |
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179. |
ECCT/23/04/02 | Shigella 53G study in Kenya Safety and feasibility of a Shigella sonnei 53G controlled human infection model in Kenyan adults: a dose finding and dose verification study |
Principal Investigator(s) 1. Melissa Kapulu 2. Fredrick Sawe Site(s) in Kenya KEMRI-Wellcome Trust Research Programme (KWTRP) Centre for Geographic Medical Research - Coast (CGMRC), Kilifi, Kenya. |
21-08-2024 |
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180. |
ECCT/23/05/02 | A5384 A Phase II, Randomized, Open-Label Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents with Tuberculous Meningitis: Improved Management with Antimicrobial AGents Isoniazid rifampiciN LinEzolid for TBM (IMAGINE-TBM) |
Principal Investigator(s) 1. Abraham Siika Site(s) in Kenya 1. Moi University Clinical Research Centre (Uasin Gishu county) 2. KEMRI Walter Reed Project (Kericho county) |
12-10-2023 |
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