Clinical Trial Applications - Approved: Filter, Search, and view applications
| # | Protocol No | Study Title | Investigator(s) & Site(s) | Date Approved | |
|---|---|---|---|---|---|
131. |
ECCT/24/02/02 | Sabin 003 A Phase 2, Randomized, Double-blind, Placebo-Controlled Trial to Evaluate Safety, Tolerability, and Immune Responses of an Investigational Monovalent Chimpanzee Adenoviral-Vectored Sudan Ebolavirus Vaccine in Healthy Adults |
Principal Investigator(s) 1. Prof. Videlis Nduba Nzioka Site(s) in Kenya KEMRI / CRDR, KEMRI Clinical Research Annex, Siaya County Referral Hospital Ground. P.O BOX 144-40600 ,Siaya, Kenya |
23-04-2024 |
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132. |
ECCT/24/02/06 | INAVO122 A phase III, multicenter, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of Inavolisib in combination with Phesgo versus placebo in combination with Phesgo as maintenance therapy after first line induction therapy in participants with PIK3CAâ€mutated HER2â€positive locally advanced or metastatic breast cancer |
Principal Investigator(s) 1. Dr Sitna Ali Site(s) in Kenya University of Nairobi -Institute of Tropical and Infectious Diseases |
03-07-2024 |
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133. |
ECCT/24/02/09 | pionERA This is a Phase III, randomized, open-label multicenter study that will evaluate the efficacy and safety of giredestrant compared with fulvestrant, both in combination with the investigator's choice of a CDK4/6 inhibitor (palbociclib, ribociclib or abemaciclib), in participants with estrogen receptor-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-) advanced breast cancer who have developed resistance to adjuvant endocrine therapy. |
Principal Investigator(s) 1. Dr Sitna Ali Site(s) in Kenya University of Nairobi -Institute of Tropical and Infectious Diseases |
04-08-2024 |
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134. |
ECCT/24/01/03 | Doxy Short Course A Phase 4 Study of a 3-Day Vs. 7-Day Regimen of Doxycycline for the Treatment of Chlamydial Infection. |
Principal Investigator(s) 1. Jackson Nyangaresi Nyandoro 2. Nelly Rwamba Mugo Site(s) in Kenya 1. Pwani Research Centre (Mombasa county) 2. KEMRI CCR-PHRD (Nairobi City county) |
18-06-2024 |
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135. |
ECCT/24/01/01 | SAVIS A Phase 1 Clinical Study to Evaluate the Safety and Immunogenicity of a Novel GMMA Vaccine Against Invasive Non-Typhoidal Salmonella in healthy Kenyan adults. |
Principal Investigator(s) 1. ANTHONY SCOTT Site(s) in Kenya KEMRI Centre for Geographical Medicine Research Coast |
15-04-2024 |
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136. |
ECCT/23/12/05 | Annovera Acceptability Study Assessing acceptability of Annovera contraceptive vaginal ring use (compared to other contraceptive method use) among women seeking family planning services |
Principal Investigator(s) 1. Elizabeth Anne Bukusi Site(s) in Kenya KEMRI-CMR-RCTP Nairobi |
17-03-2024 |
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137. |
ECCT/24/01/02 | AP Implementation Research Implementation of WHO recommendations for drugs and approaches to prevent and treat postpartum hemorrhage: a multi-country feasibility, acceptability and cost-effectiveness study |
Principal Investigator(s) 1. Daisy Ruto Jerop Ruto Site(s) in Kenya 36 public health facilities in Makueni County |
30-05-2024 |
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138. |
ECCT/23/12/02 | PEARL RSVt Vaccine Study Phase III, randomized, observer-blind, placebo-controlled, multi-center, multinational study to evaluate the efficacy, immunogenicity, and safety of a Respiratory Syncytial Virus vaccine in infants and toddlers (PEARL) |
Principal Investigator(s) 1. Dr. Maricianah Onono Site(s) in Kenya 1. Victoria Biomedical Research Institute (VIBRI) (Kisumu county) 2. Walter Reed Army Institute of Research -Kericho Site (Kericho county) 3. KEMRI CCR – Butere Clinical Research Centre (Kakamega county) 4. Siaya County Referral Hospital (SCRH) (Siaya county) 5. Kenya Medical Research Institute Center for Microbiology Research (CMR) (Kisumu county) 6. KAVI - Institute of Clinical Research (KAVI - ICR) (Nairobi City county) 7. Kombewa Clinical Research Center, KEMRI, (Kisumu county) |
10-05-2024 |
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139. |
ECCT/24/03/05 | 221163 PALISADE Long-Term Follow-Up of CAB LA for Participants in HPTN 083 and HPTN 084 CAB PrEP Studies at Risk of HIV Acquisition |
Principal Investigator(s) 1. Grace Mboya Site(s) in Kenya KEMRI Kisumu Clinical Research Site |
10-05-2024 |
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140. |
ECCT/23/12/01 | PEARL RSVt Vaccine Study Phase III, randomized, observer-blind, placebo-controlled, multi-center, multinational study to evaluate the efficacy, immunogenicity, and safety of a Respiratory Syncytial Virus vaccine in infants and toddlers (PEARL) |
Principal Investigator(s) 1. Prof Walter Jaoko 2. Dr. Lucas Thina Otieno 3. Prof. Kariuki Simon 4. Dr. Janet Nyawira Oyieko 5. Walter Otieno 6. Onono Dr. Marcianah 7. Dr. Lucas Thina Otieno 8. Prof. Kariuki Simon 9. Dr. Janet Nyawira Oyieko 10. Walter Otieno 11. Onono Dr. Marcianah Site(s) in Kenya 1. KAVI-Institute of Clinical Research, University of Nairobi (Nairobi City county) 2. Victoria Biomedical Research Institute (VIBRI) (Kisumu county) 3. Walter Reed Army Institute of Research -Kericho Site (Kericho county) 4. KEMRI CCR – Butere Clinical Research Centre (Kakamega county) 5. Siaya County Referral Hospital (SCRH (Siaya county) 6. Kenya Medical Research Institute Center for Microbiology Research (CMR (Kisumu county) 7. Kombewa Clinical Research Center, KEMRI, (Kisumu county) |
02-05-2024 |
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