Clinical Trial Applications - Approved: Filter, Search, and view applications
| # | Protocol No | Study Title | Investigator(s) & Site(s) | Date Approved | |
|---|---|---|---|---|---|
11. |
ECCT/26/02/03 | REVIVE Study - KNH A randomised, double blinded, placebo-controlled, multicentre trial of azithromycin prophylaxis for advanced HIV disease |
Principal Investigator(s) 1. Loice Achieng Ombajo Site(s) in Kenya 1. Kenyatta National Hospital (KNH) (Nairobi City county) |
28-09-2026 |
View |
12. |
ECCT/26/02/04 | RSV IMPACT TRIAL A Phase-IIIb individually randomized, placebo-controlled trial on safety of RSVA/B-preF vaccine in pregnant women and efficacy against severe RSV-associated lower respiratory tract infection (LRTI) in infants. |
Principal Investigator(s) 1. Joyce Uchi Nyiro 2. Makobu Kimani Site(s) in Kenya 1. Kilifi, KEMRI-Centre for Geographic Medicine Research Coast (CGMRC) (Kilifi county) |
28-05-2026 |
View |
13. |
ECCT/25/12/04 | Floral Study An open-label, multi-centre, rollover study to characterise long-term safety and efficacy of etavopivat in adults, adolescents and children who have sickle cell disease or thalassaemia and have completed a treatment period in an etavopivat study |
Principal Investigator(s) 1. Walter Otieno Site(s) in Kenya 1. Kombewa Clinical Research Center (Kisumu county) 2. KEMRI Kondele Children\'s Hospital (Kisumu county) 3. Center for Research in Therapeutic Sciences (CREATES) (Kisumu county) 4. KEMRI Siaya Clinical Research Annex (Siaya county) 5. KEMRI WALTER REED KERICHO (Kericho county) 6. Getrude\'s Children\'s Hospital (Nairobi City county) |
13-04-2026 |
View |
14. |
ECCT/25/12/02 | ITU512 Study - Site 6003 A Phase I/II clinical study to investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of ITU512 in healthy participants and patients with sickle cell disease |
Principal Investigator(s) 1. Godfrey Allan Otieno Site(s) in Kenya 1. Site 6001: International Cancer Institute (Uasin Gishu county) 2. Site 6002: Gertrude’s Children’s Hospital (Nairobi City county) 3. Site 6003: KEMRI Kondele Children’s Hospital (Kisumu county) |
23-10-2026 |
View |
15. |
ECCT/25/12/03 | ITU512 Study - Site 6002 A Phase I/II clinical study to investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of ITU512 in healthy participants and patients with sickle cell disease |
Principal Investigator(s) 1. Doreen Terry Karimi Mutua Site(s) in Kenya 1. Site 6001: International Cancer Institute (Uasin Gishu county) 2. Site 6002: Gertrude’s Children’s Hospital (Nairobi City county) 3. Site 6003: KEMRI Kondele Children’s Hospital (Kisumu county) |
23-10-2026 |
View |
16. |
ECCT/25/11/05 | MK-8527-011 Study A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis |
Principal Investigator(s) 1. Dr. Joshua Kimani Site(s) in Kenya 1. Nyanza Reproductive Health Society (NRHS), UNIM Research and Training Centre (URTC) (Kisumu county) 2. Partners for Health and Development in Africa – Sex workers Outreach Program (PHDA – SWOP) Clinic- Nairobi, Kenya (Nairobi City county) 3. Kenya Impact Research and Development Organization (K-IRDO) (Kisumu county) |
05-03-2026 |
View |
17. |
ECCT/26/04/02 | IGHID 12430/DELIVER-02 IGHID12430/DELIVER-02 - A PHASE 1, OPEN LABEL,STUDY TO EVALUATE THE SAFETY AND TOLERABILITY OF MGD014 AND MGD020 WITH A LATENCY REVERSAL AGENT VERSUS TEMPORARY TREATMENT INTERRUPTION IN PERSONS WITH HIV-1 ON ANTIRETROVIRAL THERAPY |
Principal Investigator(s) 1. Charity Wambui Kanyoro Site(s) in Kenya 1. Moi University Clinical Research Centre(MUCRC), Eldoret, Kenya (Uasin Gishu county) 2. Kericho Clinical Research Center (Kericho CRC), Kericho, (Kericho county) |
25-06-2026 |
View |
18. |
ECCT/25/12/05 | Floral Study An open-label, multi-centre, rollover study to characterise long-term safety and efficacy of etavopivat in adults, adolescents and children who have sickle cell disease or thalassaemia and have completed a treatment period in an etavopivat study |
Principal Investigator(s) 1. Janet Oyieko Site(s) in Kenya 1. Kombewa Clinical Research Center (Kisumu county) 2. Center for Research in Therapeutic Sciences (CREATES) (Kisumu county) 3. Gertrude\'s Children\'s Hospital (Nairobi City county) 4. KEMRI Siaya Clinical Research Annex (Siaya county) 5. KEMRI WALTER REED KERICHO (Kericho county) 6. KEMRI Kondele Children\'s Hospital (Kisumu county) |
13-04-2026 |
View |
19. |
ECCT/25/11/02 | DELIVER-02 IGHID 12430/DELIVER-02 - A PHASE 1, OPEN LABEL,STUDY TO EVALUATE THE SAFETY AND TOLERABILITY OF MGD014 AND MGD020 WITH A LATENCY REVERSAL AGENT VERSUS TEMPORARY TREATMENT INTERRUPTION IN PERSONS WITH HIV-1 ON ANTIRETROVIRAL THERAPY |
Principal Investigator(s) 1. Deborah Chepngeno Langat Site(s) in Kenya 1. Kericho Clinical Research Center (Kericho CRC), Kericho, (Kericho county) 2. MOI UNIVERSITY CLINICAL RESEARCH CENTRE (MUCRC), ELDORET (Uasin Gishu county) |
25-06-2026 |
View |
20. |
ECCT/25/11/07 | MK-8527 as HIV-1 PrEP Protocol Title: A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis |
Principal Investigator(s) 1. John Mark Ayallo 2. Kelvin Jerry Wandera 3. John Okanda 4. Joash Diemo 5. Tobias Odwar 6. Jacob Onyango Site(s) in Kenya 1. Kenya Impact Research and Development Organization (K-IRDO) (Kisumu county) 2. Nyanza Reproductive Health Society (NRHS), UNIM Research and Training Center (URTC) (Kisumu county) 3. Partners for Health and Development in Africa – Sex workers Outreach Program (PHDA – SWOP) (Nairobi City county) |
09-02-2026 |
View |