Clinical Trial Applications - Approved: Filter, Search, and view applications
| # | Protocol No | Study Title | Investigator(s) & Site(s) | Date Approved | |
|---|---|---|---|---|---|
31. |
ECCT/15/02/03 | IVERMAL study Efficacy and safety of high-dose Ivermectin for reducing malaria transmission: A dose finding study |
Principal Investigator(s) 1. Menno Roderick Smit Site(s) in Kenya 1. Jaramogi Oginga Odinga Teaching and Referral Hospital (JOOTRH) (Kisumu county) 2. Kisumu District Hospital (KDH), (Kisumu county) 3. Siaya District Hospital (Siaya county) 4. Vihiga District Hospital (Vihiga county) |
26-03-2015 |
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32. |
ECCT/15/03/01 | A phase III, non-inferiority trial using Carbetocin room temperature stable (RTS) for the prevention of postpartum haemorrhage during the third stage of labour in women delivering A phase III, randomized, double-blind, active, controlled, multinational, multicentre, non-inferiority trial using Carbetocin room temperature stable (RTS) for the prevention of postpartum haemorrhage during the third stage of labour in women delivering vaginally. |
Principal Investigator(s) 1. Zahida Qureshi Site(s) in Kenya Kenyatta National Hospital |
27-07-2015 |
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33. |
ECCT/15/06/03 | DolutegrAvir With NRTIs as second-line treatment (DAWNING) A Phase 3b, randomised, open-label study of the antiviral activity and safety of dolutegravir compared to lopinavir/ritonavir both administered with dual nucleoside reverse transcriptase inhibitor therapy in HIV-1 infected adult subjects with treatment failure on first line therapy |
Principal Investigator(s) 1. Dr. Evans Inyangala Amukoye 2. Dr. Maricianah Atieno Onono Site(s) in Kenya 1. Center for Respiratory Diseases Research, CRDR, KEMRI, Nairobi (Nairobi City county) 2. KEMRI-Research Care and Training Program (RCTP), Family AIDS Care and Education Services (FACES), Lumumba health centre (Kisumu county) |
29-07-2015 |
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34. |
ECCT/14/08/03 | STAND Study (Shortening Treatment by Advancing Novel Drugs) Long Title: A Phase 3 Open Label Partially Randomised Trial to Evaluate the Efficacy, Safety and Tolerability of the Combination of Moxifloxacin plus PA-824 plus Pyrazinamide after 4 and 6 months of Treatment in Adult Subjects with Drug Sensitive Smear Positive Pulmonary Tuberculosis and after 6 months of Treatment in Adult Subjects with Multi-Drug Resistant, Smear-Positive Pulmonary Tuberculosis Short Title: STAND Study (Shortening Treatment by Advancing Novel Drugs) |
Principal Investigator(s) 1. Dr Videlis Nduba 2. Dr Evans Amukoye Site(s) in Kenya 1. KEMRI-CRDR(East Nairobi) (Nairobi City county) 2. KEMRI-CRDR(West Nairobi) (Nairobi City county) |
17-08-2015 |
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35. |
ECCT/15/06/01 | Pyronaridine-artesunate and artemether-lumefantrine for the treatment of paediatric uncomplicated falciparum malaria in Western Kenya |
Principal Investigator(s) 1. Patrick Sawa Site(s) in Kenya St. Judes Clinic, ICIPE |
04-09-2015 |
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36. |
ECCT/14/09/01 | Extension to study MALARIA-055 PRI (110021) for evaluation of long-term efficacy, safety and immunogenicity of GSK Biologicals’candidate malaria vaccine (SB257049) in infants and children in Africa An open extension to the phase III, multi-center study MALARIA-055 PRI (110021) to evaluate long-term efficacy, safety and immunogenicity of the RTS,S/AS01E candidate vaccine against malaria disease caused by Plasmodium falciparum in infants and children in Africa. Study number: MALARIA-076 (200599) |
Principal Investigator(s) 1. Walter Otieno Site(s) in Kenya Kenya Medical Research Institute/Walter Reed Project |
23-09-2015 |
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37. |
ECCT/15/12/05 | Post-discharge Malaria Chemoprevention(PMC) study Malaria Chemoprevention with monthly treatment with dihydroartemisinin-piperaquine for the post-discharge management of severe anaemia in children aged less than 5 years in Uganda and Kenya: A 3-year, multi-centre, parallel-group, two-arm randomised placebo controlled superiority trial |
Principal Investigator(s) 1. Titus Kwambai 2. Simon Kariuki Site(s) in Kenya 1. Siaya County Referral Hospital (Siaya county) 2. Homa Bay County Referral Hospital (Homa Bay county) 3. Migori County Referral Hospital (Migori county) 4. Busia County Referral Hospital (Busia county) |
24-02-2016 |
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38. |
ECCT/15/12/02 | The Evidence for Contraceptive options and HIV Outcomes (ECHO) Trial A Multi Centre, Open label, Randomized Clinical Trial, Comparing HIV incidence and Contraceptive Benefits in Women using Depot Medroxyprogesterone Acetate, Levernogestrel (LNG) implant and Copper Intrauterine Devices (IUD). Short Title : The Evidence for Contraceptive options and HIV Outcomes (ECHO) Trial |
Principal Investigator(s) 1. Prof Elizabeth Anne Bukusi Site(s) in Kenya KEMRI-RCTP Study center , Lumumba |
11-04-2016 |
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39. |
ECCT/15/08/01 | Rifapentine During Intensive Phase TB Treatment Rifapentine-containing treatment shortening regimens for pulmonary tuberculosis: a randomized, open-label, controlled, phase 3 clinical trial |
Principal Investigator(s) 1. Elisha Ochieng Okeyo Site(s) in Kenya KEMRICDC, KISUMU, KENYA |
05-05-2016 |
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40. |
ECCT/15/11/01 | A5264 A Randomized Evaluation of Antiretroviral Therapy Alone or with Delayed Chemotherapy versus Antiretroviral Therapy with Immediate Adjunctive Chemotherapy for Treatment of Limited Stage AIDS-KS in Resource-Limited Settings (REACT-KS) |
Principal Investigator(s) 1. Dr. Victor Otieno Mudhune Site(s) in Kenya 1. KEMRI CDC (Kisumu county) |
05-05-2016 |
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