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Page 80 of 104, showing 5 Applications out of 518 total, starting on record 396, ending on 400

# Protocol No Study Title Investigator(s) & Site(s)

396.

ECCT/17/08/09   A trial to compare two new combinations of antimalarial drugs with the standard combination of antimalarial drugs in Kenyan children
    An open-label randomised trial to assess the therapeutic efficacy and tolerability of arterolane-piperaquine plus single low dose primaquine versus arterolane-piperaquine plus mefloquine and single low dose primaquine versus artemether-lumefantrine plus single low dose primaquine in the treatment of uncomplicated falciparum malaria in children in Kenya.   
Principal Investigator(s)
1. Philip Bejon
Site(s) in Kenya
1. Kilifi County Hospital - Paediatric Out patient and Inpatient department (Kilifi county)
2. Pingilikani Dispensary (Kilifi county)
 
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397.

ECCT/25/01/01   FLORAL
    An open-label, multi-centre, rollover study to characterise long-term safety and efficacy of etavopivat in adults, adolescents and children who have sickle cell disease or thalassaemia and have completed a treatment period in an etavopivat study.   
Principal Investigator(s)
1. Bernhard Ogutu
Site(s) in Kenya
1. Center for Research in Therapeutic Sciences (CREATES) (Kisumu county)
2. Gertrude’s Children’s Hospital (Nairobi City county)
3. KEMRI Siaya Clinical Research Annex (Siaya county)
4. KEMRI/ WRAIR-Africa, Kombewa Clinical Research Center (Kisumu county)
5. KEMRI WALTER REED KERICHO (Kericho county)
6. KEMRI Kondele Children\'s Hospital (Kisumu county)
7. KEMRI/ WRAIR-Africa, Kombewa Clinical Research Center (Kisumu county)
 
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398.

ECCT/19/04/03   Phase III pediatric study with the L-PZQ ODTs
    An Open-label, Phase 3 efficacy and safety study of L-praziquantel orodispersible tablets (L-PZQ ODT) in Schistosoma-infected children 3 months to 6 years of age, including a 2:1 randomized, controlled cohort of Schistosoma mansoni-infected children 4 to 6 years of age treated with L-PZQ ODT or commercial PZQ (Biltricide®)   
Principal Investigator(s)
1. Maurice Reuben Odiere
Site(s) in Kenya
KEMRI-Centre for Global Health Research (CGHR)
 
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399.

ECCT/12/08/01   Partners Demonstration Project
    An open-label, pilot demonstration and evaluation project of antiretrovira-based HIV-1 prevention among high-risk HIV-1 serodiscordant African couples.   
Principal Investigator(s)
1. Dr. Nelly Rwamba Mugo
Site(s) in Kenya
1. Partners in Prevention, Thika Site (Kiambu county)
2. Partners in Prevention, Kisumu Site (Kisumu county)
 
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400.

ECCT/13/03/02   An open-label, pilot demonstration and evaluation project of antiretroviral-based HIV-1 prevention among high-risk HIV-1 serodiscordant African couples
    An open-label, pilot demonstration and evaluation project of antiretroviral-based HIV-1 prevention among high-risk HIV-1 serodiscordant African couples The Partners PrEP Study Demonstration Project   
Principal Investigator(s)
1. DR.ELIZABETH ANNE BUKUSI ELIZABETH ANNE BUKUSI
Site(s) in Kenya
1. THIKA (Nairobi City county)
 
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