Clinical Trial Applications - Approved: Filter, Search, and view applications
| # | Protocol No | Study Title | Investigator(s) & Site(s) | Date Approved | |
|---|---|---|---|---|---|
531. |
ECCT/25/05/08 | Floral roll over study An open-label, multi-centre, rollover study to characterise long-term safety and efficacy of etavopivat in adults, adolescents and children who have sickle cell disease or thalassaemia and have completed a treatment period in an etavopivat study. |
Principal Investigator(s) 1. Prof Videlis Nduba Site(s) in Kenya 1. KEMRI Siaya Clinical Research Annex (Siaya county) 2. Center for Research in Therapeutic Sciences (CREATES) (Kisumu county) 3. Gertrudes Childrens Hospital (Nairobi City county) 4. KEMRI/ WRAIR-Africa, Kombewa Clinical Research Center (Kisumu county) 5. KEMRI WALTER REED KERICHO (Kericho county) 6. KEMRI/ WRAIR-Africa, Kombewa Clinical Research Center (Kisumu county) 7. KEMRI Kondele Children\'s Hospital (Kisumu county) |
05-03-2026 |
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532. |
ECCT/25/05/10 | Field Evaluation for STI POC Evaluation of a Point-of-Care (PoC) diagnostic device to improve sexually Transmitted Infections Management and outcomes in Kenya: SERU PROTOCOL NO. NON KEMRI 5074 Enable GingerCannot connect to Ginger Check your internet connection or reload the browserDisable Ginger?How to use GingerRephraseRephrase with Ginger (Ctrl+Alt+E)Edit in GingerGinger is checking your text for mistakes...Disable Ginger in this text fieldDisable Ginger on this website× Enable GingerCannot connect to Ginger Check your internet connection or reload the browserDisable Ginger?How to use GingerRephraseRephrase with Ginger (Ctrl+Alt+E)Edit in GingerGinger is checking your text for mistakes...Disable Ginger in this text fieldDisable Ginger on this website× |
Principal Investigator(s) 1. Patricia Ongwen 2. Dismas Ouma 3. Rose Wafula Site(s) in Kenya International Centre for Reproductive Health -Kenya |
29-04-2026 |
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533. |
ECCT/25/05/11 | Sparkle study site-1406 A phase III, Multicenter, Randomized, Placebo Controlled, Double blind Study to Assess Efficacy and Safety of Crizanlizumab (5 mg/kg) versus placebo, with or without Hydroxyurea/Hydroxycarbamide Therapy, in Adolescent and Adult Sickle Cell Disease Patients with Frequent Vaso-Occlusive Crises |
Principal Investigator(s) 1. Doreen Mutua Site(s) in Kenya 1. Victoria Biomedical Research Institute (Kisumu county) 2. Ahero Clinical trials Unit (Kisumu county) 3. International Cancer institute (Uasin Gishu county) 4. Kondele Childrens Hospital (Kisumu county) 5. KEMRI/CRDR KEMRI Clinical Research Annex (Siaya county) 6. Gertrudes Children’s Hospital (Nairobi City county) |
03-02-2026 |
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534. |
ECCT/25/05/12 | SAFIRE A multicentre open-label, non-inferiority adaptive platform randomised controlled trial to evaluate the efficacy, safety, and tolerability of antimalarials for the treatment of uncomplicated malaria in the first trimester of pregnancy |
Principal Investigator(s) 1. Hellen Barsosio Site(s) in Kenya The Kenya Medical Research Institute (KEMRI), Centre for Global Health Research (CGHR) |
15-10-2025 |
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535. |
ECCT/25/05/13 | IVI CCV 002 A Phase II, randomized, controlled, age-descending study in adults and children to evaluate the safety and immunogenicity of the OSP:rTTHc Cholera Conjugate Vaccine in cholera-endemic region |
Principal Investigator(s) 1. Walter Jaoko Site(s) in Kenya KAVI - Institute of Clinical Research, University of Nairobi |
07-10-2025 |
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536. |
ECCT/25/06/01 | Neosep1 An open-label randomised controlled trial comparing novel combination and currently used antibiotic regimens for the empiric treatment of neonatal sepsis with a run-in confirmatory pharmacokinetic phase. |
Principal Investigator(s) 1. Christine Nafula Manyasi Site(s) in Kenya 1. Mbagathi County Referral Hospital (Nairobi City county) |
02-10-2025 |
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537. |
ECCT/25/06/02 | Neosep1 An open-label randomised controlled trial comparing novel combination and currently used antibiotic regimens for the empiric treatment of neonatal sepsis with a run-in confirmatory pharmacokinetic phase. |
Principal Investigator(s) 1. Nayirat Mohamed Dormohamed Site(s) in Kenya 1. Coast General Teaching and Referral Hospital (Mombasa county) |
02-10-2025 |
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538. |
ECCT/25/06/03 | ZHR-001 Physiological and Biomarker Monitoring: Enhancing Vital Signs and Biomarkers Algorithm of Binah.AI in the Kenyan Population |
Principal Investigator(s) 1. Borna Achieng Nyaoke Site(s) in Kenya Zuri Health Medical Centre |
21-11-2025 |
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539. |
ECCT/25/07/01 | FIH Study of CLY-124 A Phase 1, Randomized, Placebo-Controlled, Double Blind, Single and Multiple Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CLY-124 in Healthy Volunteers and Participants with Sickle Cell Disease |
Principal Investigator(s) 1. Bernhards Ogutu Site(s) in Kenya 1. Strathmore University Medical Center [SUMC], Creates for Research in Therapeutic Sciences (Nairobi City county) 2. Victoria Biomedical Research Institute [VIBRI] (Kisumu county) |
18-12-2025 |
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540. |
ECCT/25/07/02 | PROPS Trial Efficacy of probiotic supplementation in preterm and small for gestational age infants. A multi-centre, placebo-controlled, individually-randomised trial (Probiotics in preterm and small for gestational age infants, PROPS trial) |
Principal Investigator(s) 1. Meshack Liru Site(s) in Kenya 1. Homabay County Referral Hospital (Homa Bay county) 2. Jaramogi Oginga Odinga Teaching and Referral Hospital (Kisumu county) 3. Kisii Teaching and Referral Hospital (Kisii county) 4. Migori County Referral Hospital (Migori county) |
14-04-2026 |
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