Clinical Trial Applications - Approved: Filter, Search, and view applications
| # | Protocol No | Study Title | Investigator(s) & Site(s) | Date Approved | |
|---|---|---|---|---|---|
431. |
ECCT/17/08/01 | A trial to compare the safety and immune response of the normal full and reduced doses of yellow fever vaccines in Kenyan adults A Phase IV randomized, double blinded non-inferiority trial on the immunogenicity and safety of fractional doses of yellow fever vaccines. |
Principal Investigator(s) 1. Philip Bejon Site(s) in Kenya KEMRI Kilifi |
07-09-2017 |
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432. |
ECCT/17/08/02 | IMPROVE (Improving PRegnancy Outcomes with intermittent PReVEntive treatment in Africa) IPTp with dihydroartemisinin-piperaquine and azithromycin for malaria, sexually transmitted and reproductive tract infections in pregnancy in high sulphadoxine-pyrimethamine resistance areas in Kenya, Malawi and Tanzania: an international multi-centre 3-arm placebo-controlled trial |
Principal Investigator(s) 1. Simon Kariuki Site(s) in Kenya 1. Migori County Referral Hospital (Migori county) 2. Homa Bay County Referral Hospital (Homa Bay county) 3. Rongo Sub-County Hospital (Migori county) 4. Ahero Sub-County Hospital (Kisumu county) 5. Rabuor Sub-County Hospital (Kisumu county) |
07-09-2017 |
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433. |
ECCT/17/05/02 | The Anza Mapema Study Expanding test and treat for HIV prevention in MSM in Kisumu, Kenya: The Anza Mapema Study |
Principal Investigator(s) 1. Fredrick Odhiambo Otieno Site(s) in Kenya Anza Mapema Study Clinic |
01-09-2017 |
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434. |
ECCT/17/08/07 | Tambua Mapema Plus Impact of a novel HIV-1 RNA testing intervention to detect acute and prevalent HIV infection and reduce HIV transmission – Tambua Mapema Plus |
Principal Investigator(s) 1. Eduard J Sanders 2. Susan M Graham Site(s) in Kenya KEMRI Mtwapa Research Clinic |
25-08-2017 |
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435. |
ECCT/17/05/01 | Multicenter Study of the Accuracy of the BD MAXâ„¢MDR-TB Assay Multicenter Study of the Accuracy of the BD MAX™MDR-TB Assay for Detection of M. tuberculosis Complex and Mutations Associated with Resistance to Rifampin or Isoniazid |
Principal Investigator(s) 1. SAMUEL GURRION OUMA Site(s) in Kenya KENYA MEDICAL RESEARCH INSTITIUTE |
20-08-2017 |
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436. |
ECCT/17/05/03 | TDF IVR-002 Study Phase 1 Safety and Pharmacokinetic Study of a Polyurethane Tenofovir Disoproxil Fumarate Vaginal Ring in Sexually Active Women (TDF IVR-002) |
Principal Investigator(s) 1. Nelly Rwamba Mugo Site(s) in Kenya Partners in Health Research & Development (Thika Partners Clinical Trial Site) |
18-07-2017 |
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437. |
ECCT/17/03/05 | HOPE Sickle Cell Disease Clinical Study A Phase 3, Double-blind, Randomized, Placebo-controlled, Multicenter Study of GBT440 Administered Orally to Patients With Sickle Cell Disease |
Principal Investigator(s) 1. Videlis Nduba 2. Jessie Nyokabi Githanga Site(s) in Kenya 1. Gertrude\'s Children\'s Hospital (Nairobi City county) 2. Strathmore University Medical Center (Nairobi City county) 3. KEMRI CRDR Clinical Research clinic at Chandaria Health Center (Nairobi City county) 4. KEMRI Kondele Childrens Hospital Center for Clinical Research (Kisumu county) 5. KEMRI Clinical Research Center at Siaya County Referral Hospital (Siaya county) |
14-07-2017 |
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438. |
ECCT/17/05/04 | Ad26.Mos4.HIV Prime/Ad26.Mos4.HIV with Clade C gp140 plus adjuvant +/- Mosaic boost A randomized, parallel-group, placebo-controlled, double-blind Phase 1/2a study in healthy HIV-uninfected adults to assess safety/tolerability and immunogenicity of 2 different prime/boost regimens: priming with tetravalent Ad26.Mos4.HIV and boosting with tetravalent Ad26.Mos4.HIV and either Clade C gp140 plus adjuvant OR a combination of Mosaic and Clade C gp140 plus adjuvant |
Principal Investigator(s) 1. Josphat Kosgei Site(s) in Kenya KEMRI WALTER REED KERICHO |
07-07-2017 |
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439. |
ECCT/17/04/01 | Odón Device for assisted vaginal delivery Feasibility, safety and preliminary efficacy study of a new device (Odón Device) for assisted vaginal delivery |
Principal Investigator(s) 1. Zahida Qureshi Site(s) in Kenya Kenyatta National Hospital |
22-06-2017 |
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440. |
ECCT/17/03/03 | FLACSAM First Line Antimicrobials in Children with Complicated Severe Acute Malnutrition |
Principal Investigator(s) 1. James Berkley Site(s) in Kenya 1. Kilifi County Hospital (Kilifi county) 2. Coast General Hospital (Mombasa county) 3. Mbagathi Hospital (Nairobi City county) |
21-06-2017 |
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