Clinical Trial Applications - Approved: Filter, Search, and view applications
| # | Protocol No | Study Title | Investigator(s) & Site(s) | Date Approved | |
|---|---|---|---|---|---|
421. |
ECCT/11/07/02 | REMEMBER A5274/REMEMBER "Reducing Early Mortality and Early Morbidity by Empiric Tuberculosis Treatment Regimens" |
Principal Investigator(s) 1. Abraham Mosigisi Siika Site(s) in Kenya 1. Moi University Clinical Research Centre (Uasin Gishu county) 2. Walter Reed Project (Kericho county) |
29-10-2010 |
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422. |
ECCT/12/04/02 | Short-course RPT/INH for latent TB in HIV-infected individuals A5279: Phase III Clinical Trial of Ultra-Short-Course Rifapentine/Isoniazid for the Prevention of Active Tuberculosis in HIV-Infected Individuals with Latent Tuberculosis Infection |
Principal Investigator(s) 1. Abraham Mosigisi Siika Site(s) in Kenya 1. Moi University Clinical Research Centre (Uasin Gishu county) |
11-05-2011 |
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423. |
ECCT/12/11/03 | Rifampin-Based TB Treatment vs. Rifabutin-Based TB Treatment in HIV A5290 "A Randomized, Phase 2b Study of a Double-Dose Lopinavir/Ritonavir-Based Antiretroviral Regimen with Rifampin-Based Tuberculosis Treatment versus a Standard-Dose Lopinavir/Ritonavir-Based Antiretroviral Regimen with Rifabutin-Based Tuberculosis Treatment with or without Raltegravir in HIV-1-Infected Persons Requiring Treatment for Active TB and HIV" |
Principal Investigator(s) 1. Abraham Mosigisi Siika Site(s) in Kenya 1. Moi University Clinical Research Centre (Uasin Gishu county) |
31-01-2012 |
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424. |
ECCT/12/11/02 | Not provided A5297: An Open-Label, Proof of Concept, Randomized Trial Comparing a LPV/r-Based to an nNRTI-Based Antiretroviral Therapy Regimen for Clearance of Plasmodium falciparum Subclinical Parasitemia in HIV-infected Adults with CD4+ Counts >200 and <350 cells/mm3 |
Principal Investigator(s) 1. Abraham Mosigisi Siika Site(s) in Kenya 1. Moi University Clinical Research Centre (Uasin Gishu county) |
29-02-2012 |
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425. |
ECCT/16/08/01 | A5349/TBTC S31 A5349/TBTC S31 “Rifapentine-containing treatment shortening regimens for pulmonary tuberculosis: A randomized, open-label, controlled phase 3 clinical trial” |
Principal Investigator(s) 1. Abraham Mosigisi Siika Site(s) in Kenya 1. Moi University Clinical Research Centre (Uasin Gishu county) 2. KEMRI Walter Reed Project (Kericho county) |
13-12-2016 |
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426. |
ECCT/17/09/02 | WHO ACTION-I and ACTION-2 Trial A65913: A multi-country, multi-centre, two-arm, parallel, double-blind, placebo-controlled, randomized trial of antenatal corticosteroids for women at risk of imminent birth in the early preterm period in hospitals in low-resource countries to improve newborn outcomes A65916: A multi-country, multi-centre, two-arm, parallel, double-blind, placebo-controlled, randomized trial of antenatal corticosteroids for women at risk of imminent birth in the late preterm period in hospitals in low-resource countries to improve newborn outcomes |
Principal Investigator(s) 1. Frederick Were 2. John Kinuthia 3. Zahida Parveen Qureshi 4. Zahida Parveen Qureshi 5. Zahida Parveen Qureshi Site(s) in Kenya 1. Coast Provincial General Hospital (Mombasa Level 5 Hospital) (Mombasa county) 2. Kiambu Level 4 Hospital (Kiambu county) 3. Thika Level 5 Hospital (Kiambu county) 4. Nakuru Level 5 Hospital (Nakuru county) |
30-04-2018 |
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427. |
ECCT/14/10/02 | Acronymn: CRASH-3 Short Title: Clinical Randomisation of an Antifibrinolytic in Significant Head Injury Full Title: Tranexamic acid for the treatment of significant traumatic brain injury: an international randomised, double blind placebo controlled trial ISRCTN15088122 ClinicalTrials.gov ID: NCT01402882 |
Principal Investigator(s) 1. Kiboi Githinji Julius 2. Dullo Michael 3. Lallet Tasneem Essaji Site(s) in Kenya 1. Kenyatta National Hospital (Nairobi City county) 2. Kitui District Hospital (Kitui county) 3. The Nairobi Hospital (Nairobi City county) |
05-02-2015 |
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428. |
ECCT/21/06/01 | ACTIV-2/A5401 ACTIV-2/A5401 "Adaptive Platform Treatment Trial for Outpatients with COVID-19" (Adapt Out COVID)_ |
Principal Investigator(s) 1. Charles Meja Kwobah Site(s) in Kenya 1. Moi University Clinical Research Centre (Uasin Gishu county) 2. KEMRI Walter Reed Project (Kericho county) |
01-11-2021 |
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429. |
ECCT/21/05/03 | Adapt Out COVID Adaptive Platform Treatment trial for Outpatients with COVID-19 |
Principal Investigator(s) 1. Kawango Agot Site(s) in Kenya 1. Kenya Impact and Research Development Organization (K-IRDO) (Kisumu county) 2. KEMRI WALTER REED (Kericho county) 3. MOI UNIVERSITY CLINICAL RESEARCH CENTRE (Uasin Gishu county) 4. Kenya Medical Research Institute (Kisumu county) |
28-07-2021 |
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430. |
ECCT/23/02/02 | KARISMA An adaptive, randomized, active-controlled, open-label, sequential cohort, multicenter study to evaluate the efficacy, safety, tolerability, and pharmacokinetics of intravenous cipargamin (KAE609) in adult and pediatric participants with severe Plasmodium falciparum malaria(KARISMA – KAE609’s Role in Severe Malaria) |
Principal Investigator(s) 1. Simon Kariuki Site(s) in Kenya KEMRI-CGHR, |
01-06-2023 |
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