Clinical Trial Applications - Approved: Filter, Search, and view applications
| # | Protocol No | Study Title | Investigator(s) & Site(s) | Date Approved | |
|---|---|---|---|---|---|
331. |
ECCT/20/07/02 | RV 460 HIV Vaccine Trial A Randomized, Double-Blind Phase 1 Trial to Evaluate the Safety and Immunogenicity of Priming with Env-C Plasmid DNA Vaccine Alone, with Different Adjuvants, or with an Adjuvanted HIV Env gp145 C.6980 Protein Vaccine and Boosting with the Adjuvanted HIV Env gp145 C.6980 Protein Vaccine with or without the Env-C Plasmid DNA Vaccine in Healthy HIV Uninfected Adults in Kenya |
Principal Investigator(s) 1. Josphat Kosgei Site(s) in Kenya KEMRI/US MRDA-A/K, KERICHO |
19-10-2020 |
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332. |
ECCT/20/07/01 | Convalescent plasma trial A randomized control trial comparing convalescent plasma therapy plus standard treatment versus standard treatment alone in patients with severe COVID-19 pneumonia at a tertiary hospital |
Principal Investigator(s) 1. Dr Isaac Adembesa Kadambi Site(s) in Kenya Kenyatta University Teaching Referral and Research Hospital |
25-09-2020 |
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333. |
ECCT/20/06/09 | HIV-CORE 006 A Phase 1 Trial of ChAdOx1- and MVA-vectored Conserved Mosaic HIV-1 Vaccines in Healthy, Adult HIV-1-negative Volunteers in Eastern and Southern Africa |
Principal Investigator(s) 1. Professor Walter Jaoko, Jaoko, Site(s) in Kenya 1. KAVI-Institute of Clinical Research (Nairobi City county) 2. KEMRI/ Wellcome Trust Research Programme (Kilifi county) |
09-09-2020 |
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334. |
ECCT/20/06/08 | E-MOTIVE TRIAL Early detection of PPH and treatment using the WHO MOTIVE ‘first response’ bundle: a cluster randomised trial with health economic analysis and mixed-methods evaluation. |
Principal Investigator(s) 1. Zahida Qureshi Site(s) in Kenya 1. Mwingi Sub county (level 4 ) hospital (Kitui county) 2. Nyeri Level 5 Hospital (Nyeri county) 3. Garissa county referral hospital (Garissa county) 4. Embu Level 5 hospital (Embu county) 5. TIGONI LEVEL 4 HOSPTIAL (Kiambu county) 6. Meru Teaching and Referral Hospital (Meru county) 7. Kitengela Sub county Hospital (Kajiado county) 8. Kakamega County Government Referral Hospital (Kakamega county) 9. Mbagathi County Hospital (Nairobi City county) 10. St. Mary\'s Mission Hospital (Nairobi City county) |
19-10-2020 |
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335. |
ECCT/20/06/07 | Quality of Oxytocin and TXA Quality of Oxytocin and Tranexamic acid in selected facilities in six countries |
Principal Investigator(s) 1. Zahida Qureshi Site(s) in Kenya 1. Mwingi Sub county (level 4 ) hospital (Kitui county) 2. Nyeri Level 5 Hospital (Nyeri county) 3. Garissa county referral hospital (Garissa county) 4. Embu Level 5 hospital (Embu county) 5. TIGONI LEVEL 4 HOSPTIAL (Kiambu county) 6. Meru Teaching and Referral Hospital (Meru county) 7. Kitengela Sub county Hospital (Kajiado county) 8. Mbagathi County Hospital (Nairobi City county) 9. Kakamega County Government Referral Hospital (Kakamega county) 10. St. Mary\'s Mission Hospital (Nairobi City county) |
19-10-2020 |
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336. |
ECCT/20/06/06 | E-MOTIVE FORMATIVE Understanding effectiveness of implementation of a postpartum haemorrhage initial response bundle |
Principal Investigator(s) 1. Zahida Qureshi Site(s) in Kenya 1. Mwingi Sub county (level 4 ) hospital (Kitui county) 2. Nyeri Level 5 Hospital (Nyeri county) 3. Garissa county referral hospital (Garissa county) 4. Embu Level 5 hospital (Embu county) 5. TIGONI LEVEL 4 HOSPTIAL (Kiambu county) 6. Meru Teaching and Referral Hospital (Meru county) 7. Kitengela Sub county Hospital (Kajiado county) 8. Kakamega County Government Referral Hospital (Kakamega county) 9. Mbagathi County Hospital (Nairobi City county) 10. St. Mary\'s Mission Hospital (Nairobi City county) |
15-10-2020 |
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337. |
ECCT/20/06/05 | SEVUSMART Trial SEVUSMART TRIAL Sevuparin as a potential adjunctive therapy in children with severe malaria |
Principal Investigator(s) 1. Kathryn Maitland Maitland Site(s) in Kenya Kilifi County Hospital |
08-08-2021 |
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338. |
ECCT/20/06/04 | ANTICOV (01 COV) An open-label, multicentre, randomised, adaptive platform trial of the safety and efficacy of several therapies, including antiviral therapies, versus control in mild /moderate cases of COVID-19 |
Principal Investigator(s) 1. Bernhards Ragama Ogutu Site(s) in Kenya 1. Mbagathi Infectious Disease Hospital (Nairobi City county) 2. Kenyatta University Teaching, Referral and Research Hospital (Nairobi City county) |
18-09-2020 |
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339. |
ECCT/20/06/03 | CVIA078 A Phase 2b randomized, open-label, controlled, single center study in Plasmodium falciparum-infected and uninfected adults age 18-55 years old in Kenya to evaluate the efficacy of the delayed, fractional dose RTS,S/AS01E malaria vaccine in subjects treated with artemisinin combination therapy plus primaquine |
Principal Investigator(s) 1. Nathanial Kelsey Copeland Site(s) in Kenya Kombewa Clinical Research Centre |
19-08-2020 |
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340. |
ECCT/20/06/02 | EMPACTA Covid19 Study A RANDOMIZED, DOUBLE-BLIND, Placebo-Controlled, MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF TOCILIZUMAB IN HOSPITALIZED PATIENTS WITH COVID‑19 PNEUMONIA |
Principal Investigator(s) 1. Reena Shah Site(s) in Kenya AgaKhan University Hospital Nairobi |
09-07-2020 |
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