Clinical Trial Applications - Approved: Filter, Search, and view applications
| # | Protocol No | Study Title | Investigator(s) & Site(s) | Date Approved | |
|---|---|---|---|---|---|
291. |
ECCT/21/05/05 | The “EMPATHY†Trial A randomized, double-blind, placebo-controlled, multicenter study of ensovibep (MP0420) in ambulatory adult patients with symptomatic COVID-19. |
Principal Investigator(s) 1. DR LUCAS OTIENO TINA 2. Dr. Bernhards Ragama Ogutu 3. Dr Deborah Chepngeno Langat 4. Dr Videlis Nduba Nduba 5. Dr Janet Oyieko Site(s) in Kenya 1. Victoria Biomedical Research Institute (VIBRI) (Kisumu county) 2. Kenyatta University Teaching Referral and Research Hospital (KUTRRH) (Nairobi City county) 3. Kenya Medical Research Institute/US Army Medical Research Directorate-Kenya-Kericho (Kericho county) 4. KEMRI, Centre for Respiratory Diseases Research (CRDR) (Nairobi City county) 5. KEMRI-USAMRD-A, Kisumu Field Station (Kisumu county) |
11-08-2021 |
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292. |
ECCT/20/06/05 | SEVUSMART Trial SEVUSMART TRIAL Sevuparin as a potential adjunctive therapy in children with severe malaria |
Principal Investigator(s) 1. Kathryn Maitland Maitland Site(s) in Kenya Kilifi County Hospital |
08-08-2021 |
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293. |
ECCT/19/11/01 | A study to determine if candidate malaria vaccines are safe, effective, and induce immunity among Kenyan adults. Safety, immunogenicity, and efficacy of R21/Matrix M (R21/MM) and ChAd63/MVA-ME-TRAP in the context of controlled human malaria infection: A Phase IIb Trial in Kenyan Adults. |
Principal Investigator(s) 1. Melissa Kapulu Site(s) in Kenya KEMRI-Wellcome Trust Research Programme (KWTRP) Centre for Geographic Medical Research - Coast (CGMRC), Kilifi, Kenya. |
07-08-2021 |
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294. |
ECCT/21/03/06 | P2026 Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs during Pregnancy and Postpartum |
Principal Investigator(s) 1. Dr. Lucy Chepkurui Koech Site(s) in Kenya KENYA MEDICAL RESEARCH INSTITUTE/WALTER REED PROJECT CLINICAL RESEARCH CENTER |
07-08-2021 |
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295. |
ECCT/21/03/05 | Unithiol Phase I TRUE-1: Trial of Repurposed Unithiol for snakebite Envenoming Phase 1 (Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Healthy Kenyan Adults) |
Principal Investigator(s) 1. Michael Abouyannis 2. Mainga Patience Mayeso Hamaluba Site(s) in Kenya KEMRI Wellcome Trust Research Programme |
07-08-2021 |
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296. |
ECCT/21/05/07 | CoVPN 3008 Multi-Center, Randomized, Efficacy Study of COVID-19 mRNA Vaccine in Regions with SARS-CoV-2 Variants of Concern |
Principal Investigator(s) 1. Grace Mboya Mugure Site(s) in Kenya 1. KEMRI CGHR Kisumu Clinical Research Site (Kisumu county) |
05-08-2021 |
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297. |
ECCT/21/05/02 | BFTAF Elderly Switch Study Switching virally suppressed HIV-1 infected elderly adults (age ≥ 60 years) without prior confirmed virological failure from current anti-retroviral regimen to bictegravir, emtricitabine and tenofovir alafenamide (B/F/TAF) |
Principal Investigator(s) 1. Loice Achieng Ombajo Site(s) in Kenya 1. Kenyatta National Hospital (Nairobi City county) 2. Jaramogi Oginga Odinga Teaching and Referral Hospital (Kisumu county) |
04-08-2021 |
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298. |
ECCT/21/06/04 | VAT00008 A parallel-group, Phase III, multi-stage, modified double-blind, multi-armed study to assess the efficacy, safety, and immunogenicity of two SARS-CoV-2 Adjuvanted Recombinant Protein Vaccines (monovalent and bivalent) for prevention against COVID-19 in adults 18 years of ageand older |
Principal Investigator(s) 1. Lucas Otieno Site(s) in Kenya 1. KEMRI-UAMRD-A/K, Kombewa Clinical Research Center (Kisumu county) 2. Kenya Medical Research Institute (Kisumu county) 3. KEMRI/Walter Reed Project Research Center (Kericho county) 4. Ganjoni Clinic (Mombasa county) 5. KEMRI/CCR Partners in Health R&D (PHRD) (Nairobi City county) 6. Kenya Medical Research Institute (Murang\'a county) 7. Moi University Clinical Research Centre (Uasin Gishu county) 8. Aga Khan University Hospital (Nairobi City county) 9. KEMRI CCR-Butere County Hospital Site (Kakamega county) |
02-08-2021 |
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299. |
ECCT/21/06/02 | VAT00008 A parallel-group, Phase III, multi-stage, modified double-blind, multi-armed study to assess the efficacy, safety, and immunogenicity of two SARS-CoV-2 Adjuvanted Recombinant Protein Vaccines (monovalent and bivalent) for prevention against COVID-19 in adults 18 years of age and older. |
Principal Investigator(s) 1. Videlis Nduba Site(s) in Kenya 1. Kenya Medical Research Institute (Nairobi City county) 2. KEMRI/Walter Reed Project Research Center-Kericho (Kericho county) 3. KEMRI-UAMRD-A/K, Kombewa Clinical Research Center-Kisumu (Kisumu county) 4. Ganjoni Clinic – Mombasa (Mombasa county) 5. KEMRI/CCR Partners in Health R&D (PHRD)-Thika (Kiambu county) 6. Kenya Medical Research Institute (Kisumu county) 7. Moi University Clinical Research Centre (Uasin Gishu county) 8. Aga Khan University Hospital-Nairobi (Nairobi City county) 9. KEMRI CCR-Butere County Hospital Site- Butere (Kakamega county) |
02-08-2021 |
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300. |
ECCT/21/06/03 | VAT00008 A parallel-group, Phase III, multi-stage, modified double-blind, multi-armed study to assess the efficacy, safety, and immunogenicity of two SARS-CoV-2 Adjuvanted Recombinant Protein Vaccines (monovalent and bivalent) for prevention against COVID-19 in adults 18 years of age and older |
Principal Investigator(s) 1. PROF.ELIZABETH ANNE BUKUSI 2. MARICIANAH A ONONO Site(s) in Kenya 1. Kenya Medical Research Institute (KEMRI) Center for Microbiology Research - Research Care and Training Program (KEMRI CMRRCTP) (Kisumu county) 2. KEMRI CCRButere County Hospital Site (Kakamega county) 3. Aga Khan University Hospital (Nairobi City county) 4. Kenya Medical Research Institute CGHR (Kisumu county) 5. Kenya Medical Research Institute (Nairobi City county) 6. KEMRI/CCR Partners in Health R&D (PHRD (Kiambu county) 7. KAVI-Institute of Clinical Research, University of Nairobi (Nairobi City county) 8. Ganjoni Clinic (Mombasa county) 9. KEMRI-UAMRD-A/K, Kombewa Clinical Research Cente (Kisumu county) 10. KEMRI/Walter Reed Project Research Center (Kericho county) |
02-08-2021 |
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