Clinical Trial Applications - Approved: Filter, Search, and view applications
| # | Protocol No | Study Title | Investigator(s) & Site(s) | Date Approved | |
|---|---|---|---|---|---|
21. |
ECCT/23/10/05 | CAPTURE-2 Phase 2a Proof-of-Concept, Multicenter, Randomized, Open Label Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of a Single Dose of the Combination M5717-pyronaridine as Chemoprevention in Asymptomatic Adults and Adolescents with Plasmodium falciparum Malaria Infection. |
Principal Investigator(s) 1. Dr Lucas Otieno Tina Otieno Tina Site(s) in Kenya Victoria Biomedical Research Institute |
16-02-2024 |
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22. |
ECCT/23/08/02 | PRAISE An Adaptive, Randomized, Placebo-controlled, Double-blind, Multi-center Study of Oral FT-4202, a Pyruvate Kinase Activator in Patients with Sickle Cell Disease (PRAISE) |
Principal Investigator(s) 1. Nduba Videlis Site(s) in Kenya 1. Getrudes Children Hospital (Nairobi City county) 2. KEMRI/CRDR (Siaya county) 3. Kombewa CRC (Kisumu county) 4. Kondele Childrens Hospital (Kisumu county) |
18-10-2023 |
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23. |
ECCT/23/10/01 | CROSSWALK Chronic (C) A RANDOMIZED DOUBLE-BLIND PHASE IIA STUDY EVALUATING THE EFFICACY, SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF CROVALIMAB AS ADJUNCT TREATMENT IN PREVENTION OF VASO-OCCLUSIVE EPISODES (VOE) IN SICKLE CELL DISEASE (SCD) (CROSSWALK-c) |
Principal Investigator(s) 1. Fredrick Chite Asirwa 2. Doreen Terry Karimi Site(s) in Kenya 1. Gertrudes Childrens Hospital (Nairobi City county) 2. International Cancer Institute (Uasin Gishu county) |
10-01-2024 |
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24. |
ECCT/23/07/04 | PRAISE An Adaptive, Randomized, Placebo-controlled, Double-blind, Multi-center Study of Oral FT-4202, a Pyruvate Kinase Activator in Patients with Sickle Cell Disease (PRAISE) |
Principal Investigator(s) 1. Dr. Janet Oyieko Site(s) in Kenya 1. Kondele Children\'s Hospital Center for Clinical Research (CCR), (Kisumu county) 2. Gertrude\'s Children Hospital (Nairobi City county) 3. KEMRI/CRDR Kemri Clinical Research Annex (Siaya county) |
28-08-2023 |
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25. |
ECCT/23/07/01 | POWWeR Health Study Single arm trial of menstrual cups among economically vulnerable women to reduce Bacterial vaginosis and STIs through reduced harmful sexual and menstrual practices (POWWeR Health Study): A Phase 2 Trial |
Principal Investigator(s) 1. Fredrick Otieno 2. Supriya Dinesh Mehta Site(s) in Kenya Nyanza Reproductive Health Society |
20-12-2023 |
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26. |
ECCT/23/07/05 | Sabin A Phase 2, Randomized, Double-blind, Placebo-Controlled Trial to Evaluate Safety, Tolerability, and Immune Responses of an Investigational Monovalent Chimpanzee Adenoviral-Vectored Marburg Virus Vaccine in Healthy Adults |
Principal Investigator(s) 1. Prof. Videlis Nduba Nduba Nzioka Site(s) in Kenya KEMRI / CRDR, KEMRI Clinical Research Annex, Siaya County Referral Hospital Ground. P.O BOX 144-40600 ,Siaya, Kenya |
11-09-2023 |
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27. |
ECCT/23/06/09 | Hibiscus Kid\'s Study A Single Arm, Open Label, Phase 1/2 Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients with Sickle Cell Disease |
Principal Investigator(s) 1. Walter Otieno 2. Videlis Nduba Site(s) in Kenya 1. Kombewa Clinical research Centre (Kisumu county) 2. KEMRI, Siaya Clinical Research Annex (Kisumu county) |
19-07-2024 |
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28. |
ECCT/23/06/08 | TSCV3000 Age-descending, randomized, placebo-controlled Phase 2 trial in three sites in sub-Saharan Africa to assess the safety and immunogenicity of a parenteral Trivalent Salmonella (S. Enteritidis/S. Typhimurium/S. Typhi Vi) Conjugate Vaccine (TSCV) versus placebo |
Principal Investigator(s) 1. RICHARD ONYANDO OMORE Site(s) in Kenya 1. SIAYA COUNTY REFERRAL HOSPITAL (Siaya county) 2. ST. ELIZABETH LWAK HOSPITAL (Siaya county) |
25-09-2023 |
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29. |
ECCT/23/06/02 | IMAGINE-TBM A Phase II, Randomized, Open-Label Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents with Tuberculous Meningitis: Improved Management with Antimicrobial AGents Isoniazid rifampiciN LinEzolid for TBM (IMAGINE-TBM). |
Principal Investigator(s) 1. Deborah Chepng\'eno Langat Site(s) in Kenya KEMRI/WRP CRC |
24-10-2023 |
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30. |
ECCT/23/10/07 | Fermented Food and Prediabetes A Study of the Hypoglycemic Effect of African Traditonal Fermented Foods amongst Prediabetic Adults. |
Principal Investigator(s) 1. Rosebella Iseme - Ondiek Site(s) in Kenya 1. Aga Khan Outreach Centre Nairobi CBD/Town (Nairobi City county) 2. Aga Khan Outreach Centre Valley Arcade (Nairobi City county) 3. Aga Khan Outreach Centre Capital Centre (Nairobi City county) 4. Aga Khan Outreach Centre Kiambu Town (Kiambu county) 5. Aga Khan Outreach Centre Juja (Kiambu county) 6. Aga Khan Outreach Centre Ruiru (Kiambu county) 7. Aga Khan Outreach Centre Ongata Rongai (Kajiado county) 8. Aga Khan Outreach Centre Ngong (Kajiado county) 9. Aga Khan Outreach Centre Kitengela (Kajiado county) |
17-01-2024 |
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