Clinical Trial Applications - Approved: Filter, Search, and view applications
| # | Protocol No | Study Title | Investigator(s) & Site(s) | Date Approved | |
|---|---|---|---|---|---|
281. |
ECCT/21/05/07 | CoVPN 3008 Multi-Center, Randomized, Efficacy Study of COVID-19 mRNA Vaccine in Regions with SARS-CoV-2 Variants of Concern |
Principal Investigator(s) 1. Grace Mboya Mugure Site(s) in Kenya 1. KEMRI CGHR Kisumu Clinical Research Site (Kisumu county) |
05-08-2021 |
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282. |
ECCT/19/11/01 | A study to determine if candidate malaria vaccines are safe, effective, and induce immunity among Kenyan adults. Safety, immunogenicity, and efficacy of R21/Matrix M (R21/MM) and ChAd63/MVA-ME-TRAP in the context of controlled human malaria infection: A Phase IIb Trial in Kenyan Adults. |
Principal Investigator(s) 1. Melissa Kapulu Site(s) in Kenya KEMRI-Wellcome Trust Research Programme (KWTRP) Centre for Geographic Medical Research - Coast (CGMRC), Kilifi, Kenya. |
07-08-2021 |
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283. |
ECCT/21/03/06 | P2026 Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs during Pregnancy and Postpartum |
Principal Investigator(s) 1. Dr. Lucy Chepkurui Koech Site(s) in Kenya KENYA MEDICAL RESEARCH INSTITUTE/WALTER REED PROJECT CLINICAL RESEARCH CENTER |
07-08-2021 |
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284. |
ECCT/21/03/05 | Unithiol Phase I TRUE-1: Trial of Repurposed Unithiol for snakebite Envenoming Phase 1 (Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Healthy Kenyan Adults) |
Principal Investigator(s) 1. Michael Abouyannis 2. Mainga Patience Mayeso Hamaluba Site(s) in Kenya KEMRI Wellcome Trust Research Programme |
07-08-2021 |
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285. |
ECCT/20/06/05 | SEVUSMART Trial SEVUSMART TRIAL Sevuparin as a potential adjunctive therapy in children with severe malaria |
Principal Investigator(s) 1. Kathryn Maitland Maitland Site(s) in Kenya Kilifi County Hospital |
08-08-2021 |
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286. |
ECCT/21/06/15 | Therapeutic Efficacy Study Efficacy of Artemether Lumefantrine (AL) and Dihydroartemisinin-Piperaquine (DHP) for the treatment of uncomplicated Plasmodium falciparum malaria in Siaya and Bungoma counties, Kenya. |
Principal Investigator(s) 1. Dr. Sarah-Blythe Ballard 2. Dr. Willis Akhwale 3. Dr. Grace Ikahu 4. Dr. George Githuka 5. Dr. Dickson Mtungu Mwakangalu 6. Dr. Elvis Omondi Oyugi 7. Hellen Gatakaa 8. Regina Jepkosgei Kandie 9. Dr. Fredrick Ouma Odhiambo Site(s) in Kenya 1. Mahonge Health Center (Bung\'oma county) 2. Kaluo Health Center (Siaya county) |
11-08-2021 |
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287. |
ECCT/21/05/06 | VAC52150EBL2010 ;Phase 2 An open label, Phase 2 study to evaluate the safety and immunogenicity of an Ad26.ZEBOV booster dose in Human Immunodeficiency Virus Positive (HIV+) adults previously vaccinated with the Ad26.ZEBOV, MVA-BN-Filo vaccine regimen |
Principal Investigator(s) 1. Prof. Omu Anzala Omu Anzala Site(s) in Kenya KAVI-institute of Clinical Research |
11-08-2021 |
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288. |
ECCT/21/05/05 | The “EMPATHY†Trial A randomized, double-blind, placebo-controlled, multicenter study of ensovibep (MP0420) in ambulatory adult patients with symptomatic COVID-19. |
Principal Investigator(s) 1. DR LUCAS OTIENO TINA 2. Dr. Bernhards Ragama Ogutu 3. Dr Deborah Chepngeno Langat 4. Dr Videlis Nduba Nduba 5. Dr Janet Oyieko Site(s) in Kenya 1. Victoria Biomedical Research Institute (VIBRI) (Kisumu county) 2. Kenyatta University Teaching Referral and Research Hospital (KUTRRH) (Nairobi City county) 3. Kenya Medical Research Institute/US Army Medical Research Directorate-Kenya-Kericho (Kericho county) 4. KEMRI, Centre for Respiratory Diseases Research (CRDR) (Nairobi City county) 5. KEMRI-USAMRD-A, Kisumu Field Station (Kisumu county) |
11-08-2021 |
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289. |
ECCT/21/06/10 | VAT00008 A parallel-group, Phase III, multi-stage, modified double-blind, multi-armed study to assess the efficacy, safety, and immunogenicity of two SARS-CoV-2 Adjuvanted Recombinant Protein Vaccines (monovalent and bivalent) for prevention against COVID-19 in adults 18 years of age and older |
Principal Investigator(s) 1. Kishorchandra Narsinh Mandaliya Site(s) in Kenya 1. Kenya Medical Research Institute (Kisumu county) 2. KEMRI/Walter Reed Project Research Center (Kericho county) 3. KEMRI/CCR Partners in Health R&D (PHRD) (Nairobi City county) 4. KEMRI CMR (Kisumu county) 5. Kenya Medical Research Institute (Nairobi City county) 6. KEMRI-UAMRD-A/K, Kombewa Clinical Research Center (Kisumu county) 7. Moi University Clinical Research Centre (Uasin Gishu county) 8. Aga Khan University Hospital (Nairobi City county) 9. KEMRI CCR-Butere County Hospital Site (Kakamega county) 10. Ganjoni Clinic (Mombasa county) |
16-08-2021 |
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290. |
ECCT/21/06/07 | VAT00008 A parallel-group, Phase III, multi-stage, modified double-blind, multi-armed study to assess the efficacy, safety, and immunogenicity of two SARS-CoV-2 Adjuvanted Recombinant Protein Vaccines (monovalent and bivalent) for prevention against COVID-19 in adults 18 years of age and older |
Principal Investigator(s) 1. Samuel Ouma Gurrion Ouma Site(s) in Kenya 1. Kenya Medical Research Institute Kisumu Clinical Research Site (Kisumu county) 2. KEMRI/Walter Reed Project Research Center (Kericho county) 3. Ganjoni Clinic (Mombasa county) 4. KEMRI/CCR Partners in Health R&D (PHRD (Nairobi City county) 5. Kenya Medical Research Institute (Nairobi City county) 6. KEMRI-UAMRD-A/K, Kombewa Clinical Research Center (Kisumu county) 7. Moi University Clinical Research Centre (Uasin Gishu county) 8. Aga Khan University Hospital (Nairobi City county) 9. KEMRI CCR-Butere County Hospital Site (Kakamega county) |
16-08-2021 |
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