Clinical Trial Applications - Approved: Filter, Search, and view applications
| # | Protocol No | Study Title | Investigator(s) & Site(s) | Date Approved | |
|---|---|---|---|---|---|
91. |
ECCT/15/06/03 | DolutegrAvir With NRTIs as second-line treatment (DAWNING) A Phase 3b, randomised, open-label study of the antiviral activity and safety of dolutegravir compared to lopinavir/ritonavir both administered with dual nucleoside reverse transcriptase inhibitor therapy in HIV-1 infected adult subjects with treatment failure on first line therapy |
Principal Investigator(s) 1. Dr. Evans Inyangala Amukoye 2. Dr. Maricianah Atieno Onono Site(s) in Kenya 1. Center for Respiratory Diseases Research, CRDR, KEMRI, Nairobi (Nairobi City county) 2. KEMRI-Research Care and Training Program (RCTP), Family AIDS Care and Education Services (FACES), Lumumba health centre (Kisumu county) |
29-07-2015 |
View |
92. |
ECCT/14/08/03 | STAND Study (Shortening Treatment by Advancing Novel Drugs) Long Title: A Phase 3 Open Label Partially Randomised Trial to Evaluate the Efficacy, Safety and Tolerability of the Combination of Moxifloxacin plus PA-824 plus Pyrazinamide after 4 and 6 months of Treatment in Adult Subjects with Drug Sensitive Smear Positive Pulmonary Tuberculosis and after 6 months of Treatment in Adult Subjects with Multi-Drug Resistant, Smear-Positive Pulmonary Tuberculosis Short Title: STAND Study (Shortening Treatment by Advancing Novel Drugs) |
Principal Investigator(s) 1. Dr Videlis Nduba 2. Dr Evans Amukoye Site(s) in Kenya 1. KEMRI-CRDR(East Nairobi) (Nairobi City county) 2. KEMRI-CRDR(West Nairobi) (Nairobi City county) |
17-08-2015 |
View |
93. |
ECCT/15/06/02 | ZINC in Sickle cell study The effects of Zinc supplementation in children with sickle cell disease in Western Kenya: a pilot study. |
Principal Investigator(s) 1. Lucas Otieno Tina Site(s) in Kenya Health Facilities in Western Kenya |
17-08-2015 |
View |
94. |
ECCT/14/09/03 | Breast Feeding Study An open-label, short-duration, repeat-dose study of breast milk excretion and infant absorption of daily oral Tenofovir Disoproxil Fumarate/Emtricitabine when used by HIV-1 uninfected lactating women |
Principal Investigator(s) 1. Jared Murray Baeten 2. Nelly Rwamba Mugo Site(s) in Kenya Partners in Prevention, Thika Site |
19-08-2015 |
View |
95. |
ECCT/15/06/01 | Pyronaridine-artesunate and artemether-lumefantrine for the treatment of paediatric uncomplicated falciparum malaria in Western Kenya |
Principal Investigator(s) 1. Patrick Sawa Site(s) in Kenya St. Judes Clinic, ICIPE |
04-09-2015 |
View |
96. |
ECCT/14/09/01 | Extension to study MALARIA-055 PRI (110021) for evaluation of long-term efficacy, safety and immunogenicity of GSK Biologicals’candidate malaria vaccine (SB257049) in infants and children in Africa An open extension to the phase III, multi-center study MALARIA-055 PRI (110021) to evaluate long-term efficacy, safety and immunogenicity of the RTS,S/AS01E candidate vaccine against malaria disease caused by Plasmodium falciparum in infants and children in Africa. Study number: MALARIA-076 (200599) |
Principal Investigator(s) 1. Walter Otieno Site(s) in Kenya Kenya Medical Research Institute/Walter Reed Project |
23-09-2015 |
View |
97. |
ECCT/15/05/02 | The TRIO Study: Acceptability of Different Multipurpose Prevention Technology (MPT) Delivery Methods (Placebo) |
Principal Investigator(s) 1. Kawango Agot Site(s) in Kenya Tuungane Youth Center Clinic |
13-10-2015 |
View |
98. |
ECCT/15/10/02 | A non-randomized, open label, single dose, pharmacokinetics, safety and tolerability study of Captopril 50mgs in healthy Kenyan Adults. |
Principal Investigator(s) 1. Bernhards Ragama Ogutu Site(s) in Kenya KEMRI centre for clinical Research |
02-12-2015 |
View |
99. |
ECCT/15/11/02 | EFFECT OF LARYNGEAL MASK AIRWAY MANOMETRY ON POST OPERATIVE SORE THROAT IN SPONTANEOUSLY BREATHING ADULT PATIENTS PRESENTING FOR SURGERY AT AGA KHAN UNIVERSITY HOSPITAL, NAIROBI. |
Principal Investigator(s) 1. Prof Vitalis Mungayi 2. Dr Edna Kemunto Gisore 3. Dr David Njoroge Waruingi Site(s) in Kenya Aga Khan University Hospital Nairobi |
02-12-2015 |
View |
100. |
ECCT/15/05/01 | Janssen Ebola vaccine study A Randomized, Observer-blind, Placebo-controlled, Phase 2 Study to Evaluate the Safety, Tolerability and Immunogenicity of Different Prime-boost Regimens of the Candidate Prophylactic Vaccines for Ebola Ad26.ZEBOV and MVA-BN-Filo in Healthy Adults, Including Elderly Subjects, HIV-infected Subjects, and Healthy Children in Two Age Strata in Africa |
Principal Investigator(s) 1. Prof Omu Aggrey Anzala Site(s) in Kenya KAVI –Institute of Clinical Research |
17-12-2015 |
View |