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# Protocol No Study Title Investigator(s) & Site(s)

1.

ECCT/25/06/02   Neosep1
    An open-label randomised controlled trial comparing novel combination and currently used antibiotic regimens for the empiric treatment of neonatal sepsis with a run-in confirmatory pharmacokinetic phase.   
Principal Investigator(s)
1. Nayirat Mohamed Dormohamed
Site(s) in Kenya
1. Coast General Teaching and Referral Hospital (Mombasa county)
 
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2.

ECCT/25/06/01   Neosep1
    An open-label randomised controlled trial comparing novel combination and currently used antibiotic regimens for the empiric treatment of neonatal sepsis with a run-in confirmatory pharmacokinetic phase.   
Principal Investigator(s)
1. Christine Nafula Manyasi
Site(s) in Kenya
1. Mbagathi County Referral Hospital (Nairobi City county)
 
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3.

ECCT/25/05/13   IVI CCV 002
    A Phase II, randomized, controlled, age-descending study in adults and children to evaluate the safety and immunogenicity of the OSP:rTTHc Cholera Conjugate Vaccine in cholera-endemic region   
Principal Investigator(s)
1. Walter Jaoko
Site(s) in Kenya
KAVI - Institute of Clinical Research, University of Nairobi
 
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4.

ECCT/25/05/12   SAFIRE
    A multicentre open-label, non-inferiority adaptive platform randomised controlled trial to evaluate the efficacy, safety, and tolerability of antimalarials for the treatment of uncomplicated malaria in the first trimester of pregnancy   
Principal Investigator(s)
1. Hellen Barsosio
Site(s) in Kenya
The Kenya Medical Research Institute (KEMRI), Centre for Global Health Research (CGHR)
 
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5.

ECCT/25/05/05   Hibiscus 2 - Site 252
    A global phase 3, randomised, double-blind and placebo-controlled study evaluating the efficacy and safety of etavopivat in adolescents and adults with sickle cell disease.   
Principal Investigator(s)
1. Videlis Nduba
Site(s) in Kenya
1. KEMRI CRDR Siaya Clinical Research Annex (Siaya county)
 
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