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Page 82 of 95, showing 5 Applications out of 471 total, starting on record 406, ending on 410

# Protocol No Study Title Investigator(s) & Site(s)

406.

ECCT/24/02/09   pionERA
    This is a Phase III, randomized, open-label multicenter study that will evaluate the efficacy and safety of   giredestrant compared with fulvestrant, both in combination with the investigator's choice of a CDK4/6 inhibitor   (palbociclib, ribociclib or abemaciclib), in participants with estrogen receptor-positive (ER+), human epidermal   growth factor receptor 2-negative (HER2-) advanced breast cancer who have developed resistance to adjuvant   endocrine therapy.   
Principal Investigator(s)
1. Dr Sitna Ali
Site(s) in Kenya
University of Nairobi -Institute of Tropical and Infectious Diseases
 
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407.

ECCT/20/12/02   MERS-201
    Study to Evaluate the Safety, Tolerability and Immunogenicity of INO-4700 for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Healthy Volunteers   
Principal Investigator(s)
1. Bernhards Ogutu
2. Josphat Kosgei
Site(s) in Kenya
1. Ahero Clinical Trials Unit (Kisumu county)
2. Kenya Medical Research Institute/Walter Reed Project (KEMRI/WRP) (Kericho county)
 
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408.

ECCT/24/04/03   SMAART-MAP trial
    Severe Malaria A Research and Trials consortium - Multisite Adaptive Platform trial   
Principal Investigator(s)
1. Prof Kathryn Maitland Maitland
Site(s) in Kenya
Kilifi County Hospital
 
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409.

ECCT/20/11/02   IAVI C100
    Safety and Pharmacokinetics of the Combination Broadly Neutralizing  Antibodies, 3BNC117-LS-J and 10-1074-LS-J, in Healthy American and   African Adults (IAVI C100)   
Principal Investigator(s)
1. Nelly Mugo
Site(s) in Kenya
1. Partners in Health Research and Development (PHRD) – CCR-KEMRI (Kiambu county)
2. Kenya AIDS Vaccine Initiative- Institute of Clinical Research (KAVI-ICR) (Nairobi City county)
 
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410.

ECCT/24/03/02   PEARL RSVt Vaccine Study
    Phase III, randomized, observer-blind, placebo-controlled, multi-center, multinational study to evaluate the efficacy, immunogenicity, and safety of a Respiratory Syncytial Virus vaccine in infants and toddlers (PEARL   
Principal Investigator(s)
1. Dr. Janet Nyawira Oyieko
Site(s) in Kenya
1. KEMRI CCR – Butere Clinical Research Centre (Kakamega county)
 
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