Clinical Trial Applications - Approved: Filter, Search, and view applications
| # | Protocol No | Study Title | Investigator(s) & Site(s) | Date Approved | |
|---|---|---|---|---|---|
381. |
ECCT/19/06/03 | Evaluation of the RTS,S vaccine implementation in Kenya (MVPE) An evaluation of the cluster-randomised pilot implementation of the RTS,S/AS01 malaria vaccine through routine health systems in western Kenya |
Principal Investigator(s) 1. Aaron Samuels Samuels Site(s) in Kenya 1. Bungoma County (Bung\'oma county) 2. Busia County (Busia county) 3. Homa Bay (Homa Bay county) 4. Kakamega County (Kakamega county) 5. Kisumu County (Kisumu county) 6. Migori County (Migori county) 7. Siaya County (Siaya county) 8. Vihiga County (Vihiga county) |
13-08-2019 |
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382. |
ECCT/19/05/01 | A randomized, double-blinded, placebo-controlled, dose-escalation phase 1 clinical trial to evaluate the safety and immunogenicity of recombinant HIV envelope protein BG505 SOSIP.664 gp140 Vaccine, Adjuvanted, in healthy, HIV--1 uninfected adults A randomized, double-blinded, placebo-controlled, dose-escalation phase 1 clinical trial to evaluate the safety and immunogenicity of recombinant HIV envelope protein BG505 SOSIP.664 gp140 Vaccine, Adjuvanted, in healthy, HIV--1 uninfected adults |
Principal Investigator(s) 1. Omu Anzala Site(s) in Kenya KAVI-ICR KNH SITE |
08-07-2019 |
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383. |
ECCT/19/02/01 | DANCE Study An Open-Label, Single Arm Study to Evaluate the Week 48 Efficacy and Safety of a Two-Drug Regimen of Dolutegravir/Lamivudine (DTG/3TC) as a Fixed Dose Combination (FDC), in Antiretroviral Therapy (ART)-Naive HIV-1-Infected Adolescents, ≥12 To <18 Years of Age who Weigh at Least 40 Kg. |
Principal Investigator(s) 1. Fredrick Odhiambo Otieno 2. Isaac Tsikhutsu Site(s) in Kenya 1. Nyanza Reproductive Health Society (Kisumu county) 2. Kenya Medical Research Institute (Kisumu county) 3. Kenya Medical Research Institute, Walter Reed Project (Kericho county) |
14-08-2019 |
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384. |
ECCT/19/01/02 | Opt4Kids Optimizing viral load suppression in Kenyan children on antiretroviral therapy (Opt4Kids) |
Principal Investigator(s) 1. Lisa Dillabaugh Abuogi 2. Patrick Oyaro Owiti Site(s) in Kenya 1. Kisumu County Hospital (Kisumu county) 2. Ahero County Hospital (Kisumu county) 3. Nyakach County Hospital (Kisumu county) 4. Lumumba sub-County Hospital (Kisumu county) 5. Jaramogi Oginga Odinga Teaching and Referral Hospital (Kisumu county) |
15-03-2019 |
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385. |
ECCT/19/01/01 | A Randomized, Open, Parallel-group, Single Dose, Phase 2a Study, to Investigate the Clinical and Parasiticidal Activity and the Pharmacokinetics of 3 dose levels of Artefenomel in combination with Ferroquine (FQ) and FQ alone, in African Patients with Unc A Randomized, Open label, Parallel-group, Single Dose Regimen, Phase 2a Study, to Investigate the Clinical and Parasiticidal Activity and the Pharmacokinetics of 3 dose levels of Artefenomel (OZ439) given in combination with Ferroquine (FQ) and FQ alone, in African Patients with Uncomplicated Plasmodium falciparum Malaria |
Principal Investigator(s) 1. Bernhards Ogutu Ragama Site(s) in Kenya 1. Ahero County hospital (Kisumu county) 2. Siaya County Hospital (Siaya county) |
13-08-2019 |
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386. |
ECCT/18/12/02 | Randomized Controlled Trial to Compare the Effect of Corn-Soy Blend + Vegetable Oil 8 and Fish Oil (CSB-VO-FO) With Corn-Soy Blend + Vegetable Oil Alone (CSB-VO) on 9 the Immunological and Microbiota Patterns among Children Aged 6 to 24 months with 10 Mod Randomized Controlled Trial to Compare the Effect of Corn-Soy Blend + Vegetable Oil 8 and Fish Oil (CSB-VO-FO) With Corn-Soy Blend + Vegetable Oil Alone (CSB-VO) on 9 the Immunological and Microbiota Patterns among Children Aged 6 to 24 months with 10 Mod |
Principal Investigator(s) 1. CHRISTOPHER L. MELBY MELBY Site(s) in Kenya KENYA MEDICAL RESEARCH INSTITUTE |
25-02-2019 |
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387. |
ECCT/18/11/02 | EPI 003 A prospective study to evaluate the safety, effectiveness and impact of the RTS,S/AS01E vaccine in young children in sub-Saharan Africa. |
Principal Investigator(s) 1. BERNHARDS OGUTU Site(s) in Kenya 1. • Ahero Clinical Trials Unit (Kisumu county) 2. KEMRI Walter Reed Army Institute of Research (Kisumu county) 3. KEMRI CDC SIAYA (Siaya county) |
25-03-2019 |
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388. |
ECCT/18/11/01 | PrIMA PrEP Implementation for Mothers in Antenatal Care |
Principal Investigator(s) 1. Grace John-Stewart John-Stewart 2. Jared Baeten Site(s) in Kenya 1. Homa Bay County - 10 sites (Homa Bay county) 2. Siaya County - 10 sites (Siaya county) |
16-05-2019 |
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389. |
ECCT/18/10/02 | Single-dose HPV catch-up vaccination efficacy: A blinded, randomized study of single-dose HPV vaccination among adolescent girls and young women in Kenya Single-dose HPV catch-up vaccination efficacy: A blinded, randomized study of single-dose HPV vaccination among adolescent girls and young women in Kenya |
Principal Investigator(s) 1. Dr. Nelly Rwamba Mugo 2. Dr. Maricianah Atieno Onono 3. Prof Bukusi Anne Bukusi 4. Dr. Betty Wanjiru Njoroge 5. Dr. Ruanne Barnabas Site(s) in Kenya 1. KEMRI NAIROBI (Nairobi City county) 2. KEMRI KISUMU (Kisumu county) 3. KEMRI THIKA PHRD (Kiambu county) |
19-11-2018 |
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390. |
ECCT/18/12/01 | study to determine if a new malaria vaccine is safe and induces immunity among Kenyan adults, young children and infants. A Phase 1b, open-label, age de-escalation, dose-escalation study to evaluate the safety and immunogenicity of different doses of a candidate malaria vaccine; adjuvanted R21(R21/MM) in adults, young children and infants in Kilifi, Kenya. |
Principal Investigator(s) 1. Mainga Hamaluba Site(s) in Kenya KEMRI-Wellcome Trust Research Programme (KWTRP) Centre for Geographic Medical Research - Coast (CGMRC), Kilifi, Kenya. |
19-03-2019 |
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