Clinical Trial Applications - Approved: Filter, Search, and view applications
| # | Protocol No | Study Title | Investigator(s) & Site(s) | Date Approved | |
|---|---|---|---|---|---|
181. |
ECCT/19/12/02 | VPM1002 Phase III PoI A multicenter, Phase III double blind, randomized active controlled study to evaluate efficacy and safety of VPM1002 in comparison with BCG in prevention of Mycobacterium tuberculosis infection in newborn infants. |
Principal Investigator(s) 1. Videlis Nduba Site(s) in Kenya 1. KEMRI-CRDR Nairobi (Nairobi City county) 2. KEMRI-CRDR Siaya (Siaya county) |
20-04-2020 |
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182. |
ECCT/19/10/01 | AMC-099 A Randomized, Placebo-Controlled Trial of HPV Vaccination to Reduce Cervical High-Grade Squamous Intraepithelial Lesions among HIV-Infected Women Participating in an HPV Test-and-Treat Program (COVENANT) |
Principal Investigator(s) 1. ELKANAH ORANGO OMENGE Site(s) in Kenya MOI UNIVERSITY CLINICAL RESEARCH CENTER |
01-04-2020 |
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183. |
ECCT/19/07/01 | IMPROVE-2 chemoprevention with monthly IPTp with dihydroartemisinin-piperaquine for malaria in HIV-infected pregnant participants on daily cotrimoxazole in Kenya and Malawi: a multi-centre placebo-controlled trial(IMPROVE-2). |
Principal Investigator(s) 1. Hellen Cherono Barsosio 2. Simon Kariuki Site(s) in Kenya 1. Ahero Sub-County Hospital (Kisumu county) 2. Rabuor Sub-County Hospital (Kisumu county) 3. Akala Sub-County Hospital (Siaya county) |
03-10-2019 |
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184. |
ECCT/19/04/02 | NADIA \"Nucleosides And Darunavir/Dolutegravir In Africa\" A randomised controlled trial of darunavir versus dolutegravir and tenofovir versus zidovudine in second-line antiretroviral therapy regimens for the public health approach in sub-Saharan Africa |
Principal Investigator(s) 1. Abraham Mosigisi Siika Site(s) in Kenya Moi University Clinical Research Centre |
12-08-2019 |
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185. |
ECCT/19/04/03 | Phase III pediatric study with the L-PZQ ODTs An Open-label, Phase 3 efficacy and safety study of L-praziquantel orodispersible tablets (L-PZQ ODT) in Schistosoma-infected children 3 months to 6 years of age, including a 2:1 randomized, controlled cohort of Schistosoma mansoni-infected children 4 to 6 years of age treated with L-PZQ ODT or commercial PZQ (Biltricide®) |
Principal Investigator(s) 1. Maurice Reuben Odiere Site(s) in Kenya KEMRI-Centre for Global Health Research (CGHR) |
18-06-2019 |
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186. |
ECCT/19/03/02 | PREVENT TD A Randomized, Placebo-Controlled, Double-Blind, Clinical Trial Evaluating Two Dose Regimens of Rifaximin (550 mg daily or 550 mg twice daily) for Chemoprophylaxis Against Travellers’ Diarrhoea (TD) Among Active Duty Deployed U.S. and British Military Personnel (PREVENT TD) |
Principal Investigator(s) 1. Flynn Alexander Site(s) in Kenya Nyati Barracks, British Army Training Unit, Kenya |
10-06-2019 |
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187. |
ECCT/19/05/03 | SEARCH Supportive Care and Antibiotics for Severe Pneumonia among Hospitalised Children |
Principal Investigator(s) 1. Ambrose Agweyu Site(s) in Kenya 1. Mama Lucy Kibaki Hospital (Nairobi City county) 2. Kiambu County Referral Hospital (Kiambu county) 3. Machakos County Referral Hospital (Machakos county) 4. Embu County Referral Hospital (Embu county) 5. Naivasha County Hospital (Nakuru county) 6. Bungoma County Referral Hospital (Bung\'oma county) 7. Busia County Referral Hospital (Busia county) 8. Kitale County Referral Hospital (Trans Nzoia county) 9. Kisumu East Hospital (Kisumu county) 10. Kakamega County Referral Hospital, Kenya (Kakamega county) |
21-07-2019 |
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188. |
ECCT/19/04/05 | PHOENIx MDR-TB A5300B/I2003B/PHOENIx "Protecting Households On Exposure to Newly Diagnosed Index Multidrug-Resistant Tuberculosis Patients" |
Principal Investigator(s) 1. Abraham Mosigisi Siika Site(s) in Kenya 1. Moi University Clinical Research Centre (Uasin Gishu county) 2. KEMRI Walter Reed Project (Kericho county) |
30-09-2019 |
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189. |
ECCT/18/07/06 | Hestia 3 A Randomised, Double-Blind, Parallel-Group, Multicentre, Phase III Study to Evaluate the Effect of Ticagrelor versus Placebo in Reducing the Rate of Vaso-Occlusive Crises in Paediatric Patients with Sickle Cell Disease |
Principal Investigator(s) 1. Prof Jessie Nyokabi Githanga 2. Videlis Nduba 3. Janet N Oyieko 4. Bernards Ragama Ogutu Site(s) in Kenya 1. Gertrude’s Children’s Hospital (Nairobi City county) 2. Chandaria Health Center Clinical Research Clinic (Nairobi City county) 3. Kenya Medical Research Institute (KEMRI) Kisumu (Kisumu county) 4. KEMRI Kombewa Clinical Research Centre (Nairobi City county) 5. Kondele Children\'s Hospital (Kisumu county) 6. Strathmore University Medical Centre (Nairobi City county) |
06-10-2018 |
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190. |
ECCT/20/11/05 | HOPE Kids 2 A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Voxelotor (GBT440) in Pediatric Participants with Sickle Cell Disease (HOPE Kids 2) |
Principal Investigator(s) 1. Jessie Nyokabi Githanga 2. Videlis Nduba 3. Bernhards Ragama Ogutu Site(s) in Kenya 1. Gertrude’s Children’s Hospital (Nairobi City county) 2. KEMRI/CRDR Clinical Research Annex (Nairobi City county) 3. Strathmore University Medical Centre (Nairobi City county) 4. KEMRI/CRDR Siaya (Siaya county) |
03-03-2021 |
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