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# Protocol No Study Title Investigator(s) & Site(s)

1.

ECCT/25/11/07   MK-8527 as HIV-1 PrEP
    Protocol Title: A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis   
Principal Investigator(s)
1. John Mark Ayallo
2. Kelvin Jerry Wandera
3. John Okanda
4. Joash Diemo
5. Tobias Odwar
6. Jacob Onyango
Site(s) in Kenya
1. Kenya Impact Research and Development Organization (K-IRDO) (Kisumu county)
2. Nyanza Reproductive Health Society (NRHS), UNIM Research and Training Center (URTC) (Kisumu county)
3. Partners for Health and Development in Africa – Sex workers Outreach Program (PHDA – SWOP) (Nairobi City county)
 
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2.

ECCT/25/11/03   RSV IMPACT TRIAL
    A Phase-IIIb individually randomized, placebo-controlled trial on safety of RSVA/B-preF vaccine in pregnant women and efficacy against severe RSV-associated lower respiratory tract infection in infants.   
Principal Investigator(s)
1. Nancy A. Otieno
2. Evans M. Ogoti
Site(s) in Kenya
Kenya Medical Research Institute, Centre for Global Health Research - Siaya (KE1)
 
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3.

ECCT/25/10/01   H06_04TP
    A Phase 2, open-label, single-center, long-term immunogenicity follow-up study of the GVGH altSonflex1-2-3 Shigella vaccine 1, 2 and 3 years   after vaccination in African children.   
Principal Investigator(s)
1. Deborah Chepngeno Langat
Site(s) in Kenya
KEMRI CRC WRP KERICHO
 
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4.

ECCT/25/09/03   PRESERVE
    Partial breast re-irradiation using ultra hypofractionation (PRESERVE) Phase 2 multi-institutional study   
Principal Investigator(s)
1. Angela Waweru
Site(s) in Kenya
Aga Khan University Hospital
 
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5.

ECCT/25/09/01   VLA1553-404
    VLA1553-404: A Pragmatic Randomised Controlled Trial to Evaluate the Effectiveness and Safety of VLA1553 against Chikungunya Virus Disease   
Principal Investigator(s)
1. Prof. Videlis Nduba
Site(s) in Kenya
1. KEMRI-MTWAPA (Kilifi county)
 
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